Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28034032 | 0.76 | L3MBTL1 (0.38) | HTTALDH1A1 | |
| SCHEMBL3066192 | 0.74 | ALOX5AP (0.46) | ALOX5APFEN1SLC22A12KCNN4MKNK2 | |
| SCHEMBL27330897 | 0.72 | NR1I2 (0.38) | ALOX5APFEN1POLBALOX15HTT | |
| SCHEMBL9440419 | 0.71 | SLC6A2 (0.44) | ALOX5APFEN1SLC22A12POLBALDH1A1 | |
| SCHEMBL26968165 | 0.70 | PTGDR2 (0.50) | — | |
| SCHEMBL13313283 | 0.70 | L3MBTL1 (0.38) | POLBHTTALDH1A1 | |
| SCHEMBL14380209 | 0.70 | LOX (0.36) | ALOX5APFEN1ALDH1A1 | |
| SCHEMBL3727145 | 0.69 | EPAS1 (0.40) | — | |
| SCHEMBL24696922 | 0.69 | ALOX5AP (0.39) | ALOX5APFEN1POLBALOX15HTT | |
| SCHEMBL30041450 | 0.69 | ALOX5AP (0.39) | ALOX5APFEN1POLBALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | BOUILLOT ANNE MARIE JEANNE | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | ALOX5AP 235/4885FEN1 2051/4885SLC22A12 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.