Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | BAX | Q07812 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232138 | 0.95 | PAX8 (0.58) | PAX8LTA4HNR1H2BAXTSHR | |
| SCHEMBL19712503 | 0.86 | PAX8 (0.50) | PAX8LTA4HNR1H2BAXTSHR | |
| SCHEMBL11712858 | 0.86 | PAX8 (0.54) | PAX8LTA4HNR1H2BAXTSHR | |
| SCHEMBL28198420 | 0.86 | PAX8 (0.50) | PAX8LTA4HNR1H2BAXTSHR | |
| SCHEMBL1006428 | 0.83 | PAX8 (0.63) | PAX8LTA4HNR1H2BAXTSHR | |
| SCHEMBL11507938 | 0.80 | AKR1C3 (0.41) | PAX8LTA4HNR1H2BAXTSHR | |
| SCHEMBL9444946 | 0.80 | TSHR (0.55) | PAX8TSHRKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL24262518 | 0.80 | KMT2A (0.61) | PAX8LTA4HNR1H2BAXTSHR | |
| SCHEMBL10712529 | 0.78 | ALDH1A1 (0.48) | PAX8TSHRKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL30034186 | 0.77 | MEN1 (0.56) | PAX8LTA4HNR1H2BAXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4208320-A | Flame retardant resin composition comprising reaction product of polyguanamine compound and cyanuric or isocyanuric acid compound | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1980-06-17 | — | — | US | claimed |
| CN-110643145-B | Resin composition and article made therefrom | 中山台光电子材料有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-113563719-A | Ternary resin blends | 劳斯莱斯有限公司 | 2021-10-29 | — | — | CN | disclosed |
| US-20100280185-A1 | HIGHLY-BRANCHED MELAMINE POLYMERS | BASF SE (DE) | 2010-11-04 | — | — | US | disclosed |
| EP-1352921-B1 | EXTRUDED STYRENE RESIN FOAM AND PROCESS FOR PRODUCING THE SAME | KANEKA CORP (JP) | 2007-02-14 | — | — | EP | disclosed |
| EP-1752486-A1 | Extruded styrene resin foam and process for producing the same | Kaneka Corporation (JP) | 2007-02-14 | — | — | EP | disclosed |
| US-6841581-B2 | Extruded styrene resin foam and process for producing the same | KANEKA CORPORATION (JP) | 2005-01-11 | — | — | US | disclosed |
| US-20030220408-A1 | Extruded styrene resin foam and process for producing the same | KANEKA CORPORATION | 2003-11-27 | — | — | US | disclosed |
| EP-1352921-A1 | EXTRUDED STYRENE RESIN FOAM AND PROCESS FOR PRODUCING THE SAME | KANEKA CORPORATION (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-5936048-A | Method for preparing modified resins and their applications | MITSUI CHEMICALS, INC. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-4891391-A | ANTIOXIDANTS, THERMOPLASTIC RESINS | MORTON THIOKOL, INC. (US) | 1990-01-02 | — | — | US | disclosed |
| EP-0281398-A2 | Phenol-stabilized microbiocidal compositions | MORTON INTERNATIONAL, INC. (US) | 1988-09-07 | — | — | EP | disclosed |
| US-4761247-A | OXIDATION RESISTANCE | MORTON THIOKOL, INC. (US) | 1988-08-02 | — | — | US | disclosed |
| US-4624679-A | Compositions containing antimicorbial agents in combination with stabilizers | MORTON THIOKOL, INC. (US) | 1986-11-25 | — | — | US | disclosed |
| US-4308196-A | HIGH MOLECULAR WEIGHT HINDERED PHENOL PHOSPHATE OR HINDERED PHENOL CYANURATE | MOBAY CHEMICAL CORPORATION (US) | 1981-12-29 | — | — | US | disclosed |
| US-4260537-A | HINDERED PHENOL OR PHENOLIC RESIN | MOBAY CHEMICAL CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
| US-4249004-A | FIREPROOFING FOR POLYMERS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1981-02-03 | — | — | US | disclosed |
| US-4208320-A | Flame retardant resin composition comprising reaction product of polyguanamine compound and cyanuric or isocyanuric acid compound | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1980-06-17 | — | — | US | disclosed |
| US-4148747-A | FOR POLYMERS | RAYCHEM CORPORATION (US) | 1979-04-10 | — | — | US | disclosed |
| US-4052279-A | HYDROXY AROMATIC COMPOUND CONTAINING SULFUR AND AN ORGANIC PHOSPHONATE AS POLYMER ANTIOXIDANT | RAYCHEM CORPORATION (US) | 1977-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280185-A1 | HIGHLY-BRANCHED MELAMINE POLYMERS | PBRM1, PARN, PARG | PAX8 2648/4885LTA4H 4167/4885NR1H2 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.