SCHEMBL373769

SCHEMBL373769

Cc1nc2ncnn2c(N)c1-c1ccc(Cl)c(Cl)c1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 8/20 0.48
KDM4E B2RXH2 2/20 0.45
MBOAT4 Q96T53 3/20 0.44
ALDH1A1 P00352 3/20 0.43
POLB P06746 1/20 0.43
IKBKB O14920 1/20 0.42
MEN1 O00255 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14491199 0.80 ALDH1A1 (0.49) MBOAT4ALDH1A1
SCHEMBL10372114 0.79 NPC1 (0.56) KDM4EMBOAT4ALDH1A1MEN1RAB9A
SCHEMBL14072898 0.77 MBOAT4 (0.39) KDM4EMBOAT4ALDH1A1POLBHTT
SCHEMBL302642 0.77 MBOAT4 (0.50) MBOAT4ALDH1A1MEN1RAB9AKMT2A
SCHEMBL14490818 0.73 KDM4E (0.56) KDM4EMBOAT4ALDH1A1MEN1RAB9A
SCHEMBL14491955 0.73 MBOAT4 (0.48) MBOAT4ALDH1A1POLBKMT2ATSHR
SCHEMBL3629809 0.72 MBOAT4 (0.45) KDM4EMBOAT4TSHR
SCHEMBL14503825 0.72 MBOAT4 (0.46) MBOAT4ALDH1A1
SCHEMBL14373948 0.71 USP2 (0.48) KDM4EMBOAT4ALDH1A1MEN1KMT2A
SCHEMBL14489594 0.71 MAPK1 (0.45) MBOAT4ALDH1A1POLBKMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2489262-B1 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-11-14 EP claimed
US-20150080215-A1 TERNARY PESTICIDAL MIXTURES BASF SE (DE) 2015-03-19 US claimed
EP-2066177-B1 FUNGICIDAL MIXTURES OF 1-METHYLPYRAZOLE-4-YLCARBOXYLIC ACID ANILIDES AND AZOLOPYRIMIDINYLAMINES BASF SE (DE) 2014-12-24 EP claimed
US-20140155263-A1 Fungicidal Mixtures Based on Azolopyrimidinylamines BASF SE (DE) 2014-06-05 US claimed
US-20130267414-A1 PESTICIDAL MIXTURES BASF SE (DE) 2013-10-10 US claimed
US-8461077-B2 Combinations of active substances BASF SE (DE) 2013-06-11 US claimed
US-20130137571-A1 Crystalline Modification of Fipronil BASF SE (DE) 2013-05-30 US claimed
EP-2552213-A2 FUNGICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES BASF SE (DE) 2013-02-06 EP claimed
US-20130023412-A1 Fungicidal Mixtures Based on Azolopyrimidinylamines BASF SE (DE) 2013-01-24 US claimed
EP-2489263-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide BASF SE (DE) 2012-08-22 EP claimed
WO-2008116730-A1 COMBINATIONS OF ACTIVE SUBSTANCES BASF SE (DE) 2008-10-02 WO claimed
US-20080234295-A1 Fungicidal Mixtures Based on Azolopyrimidinylamines BASF AKTIENGELSELLSCHAFT (DE) 2008-09-25 US claimed
WO-2008095913-A2 PESTICIDAL MIXTURES BASF SE (DE) 2008-08-14 WO claimed
WO-2008092759-A2 PESTICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES DERIVATIVES AND INSECTICIDES BASF SE (DE) 2008-08-07 WO claimed
WO-2008092836-A2 METHOD FOR IMPROVING PLANT HEALTH BASF SE (DE) 2008-08-07 WO claimed
WO-2008087182-A2 FUNGICIDAL MIXTURES OF 1-METHYLPYRAZOLE-4-YLCARBOXYLIC ACID ANILIDES AND AZOLOPYRIMIDINYLAMINES BASF SE (DE) 2008-07-24 WO claimed
EP-1909579-A1 FUNGICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES BASF SE (DE) 2008-04-16 EP claimed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
WO-2008034787-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
WO-2007012598-A1 FUNGICIDAL MIXTURES BASED ON AZOLOPYRIMIDINYLAMINES BASF AKTIENGESELLSCHAFT (DE) 2007-02-01 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130023412-A1 Fungicidal Mixtures Based on Azolopyrimidinylamines DDT, AS3MT, AADAC MAP3K14 2632/4885KDM4E 826/4885MBOAT4 3557/4885
US-20130267414-A1 PESTICIDAL MIXTURES AADAC, CTRL, AAAS MAP3K14 4599/4885KDM4E 3073/4885MBOAT4 3142/4885
US-20140155263-A1 Fungicidal Mixtures Based on Azolopyrimidinylamines DDT, STS, ARSA MAP3K14 3260/4885KDM4E 1223/4885MBOAT4 4718/4885
US-20080234295-A1 Fungicidal Mixtures Based on Azolopyrimidinylamines DDT, STS, ARSA MAP3K14 3260/4885KDM4E 1223/4885MBOAT4 4718/4885
US-20130137571-A1 Crystalline Modification of Fipronil FIP1L1, PTMS, FIBP MAP3K14 3522/4885KDM4E 1922/4885MBOAT4 4595/4885
US-20150080215-A1 TERNARY PESTICIDAL MIXTURES AADAC, AS3MT, DDT MAP3K14 4532/4885KDM4E 2309/4885MBOAT4 3224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.