Naphthalene

Naphthalene

SCHEMBL373901

O=C(O)O.O=C(O)O.c1ccc2ccccc2c1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Naphthalene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.61
ALOX12 P18054 1/20 0.61
ALDH1A1 P00352 4/20 0.50
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
TSHR P16473 2/20 0.50
DAO P14920 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
ALOX15 P16050 1/20 0.50
CYP2C19 P33261 2/20 0.48
HSD17B10 Q99714 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
NR4A1 P22736 1/20 0.48
NR4A2 P43354 1/20 0.48
NR4A3 Q92570 1/20 0.48
KDM4E B2RXH2 1/20 0.48
CYP1A2 P05177 1/20 0.48
GLA P06280 1/20 0.48
HPGD P15428 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL1478520 1.00 CYP2A6 (0.61) CYP2A6ALOX12ALDH1A1CES2CES1
Naphthalene SCHEMBL3278833 1.00 CYP2A6 (0.61) CYP2A6ALOX12ALDH1A1CES2CES1
Naphthalene SCHEMBL7201843 1.00 CYP2A6 (0.61) CYP2A6ALOX12ALDH1A1CES2CES1
Naphthalene SCHEMBL10590639 1.00 CYP2A6 (0.61) CYP2A6ALOX12ALDH1A1CES2CES1
Naphthalene SCHEMBL27604963 0.89 CYP2A6 (0.57) CYP2A6ALOX12ALDH1A1CES2CES1
Naphthalene SCHEMBL10438031 0.88 CYP2A6 (0.80) CYP2A6ALOX12ALDH1A1CES2CES1
Naphthalene SCHEMBL11145450 0.88 CYP2A6 (0.80) CYP2A6ALOX12ALDH1A1CES2CES1
Anthracene SCHEMBL3911533 0.86 ALDH1A1 (0.56) ALDH1A1CES2CES1TSHRDAO
Naphthalene SCHEMBL1348831 0.86 CYP2A6 (0.53) CYP2A6ALOX12ALDH1A1CES2CES1
Anthracene SCHEMBL29071655 0.86 ALDH1A1 (0.56) ALDH1A1CES2CES1TSHRDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2548715-B1 Laser welding method and moulded parts made therefrom EMS PATENT AG (CH) 2017-04-05 EP claimed
EP-2548714-B1 Laser welding method and parts made thereby EMS PATENT AG (CH) 2013-09-11 EP claimed
EP-2410020-B1 Partially aromatic polyamide moulding compositions and their applications EMS PATENT AG (CH) 2013-01-30 EP claimed
US-20130022766-A1 LASER BEAM WELDING METHOD AND MOLDED COMPONENTS FABRICATED THEREBY EMS-PATENT AG (CH) 2013-01-24 US claimed
EP-2410020-A1 Partially aromatic polyamide moulding compositions and their applications EMS-PATENT AG (CH) 2012-01-25 EP claimed
EP-2209841-A1 ELECTRICAL INSULATION SYSTEM ABB Research Ltd. (CH) 2010-07-28 EP claimed
WO-2009062873-A1 ELECTRICAL INSULATION SYSTEM ABB RESEARCH LTD (CH) 2009-05-22 WO claimed
WO-2009062543-A1 FIBER-REINFORCED COMPOSITE SYSTEM AS ELECTRICAL INSULATION ABB RESEARCH LTD (CH) 2009-05-22 WO claimed
EP-1775647-A1 DIAL OF SOLAR CLOCK AND CLOCK SEIKO EPSON CORPORATION (JP) 2007-04-18 EP claimed
US-20060028920-A1 Solar battery timepiece dial plate and timepiece SEIKO EPSON CORPORATION (JP) 2006-02-09 US claimed
EP-1220826-B1 PROCESS FOR THE RECOVERY OF DISPROPORTIONATION REACTION PRODUCTS MOSSI & GHISOLFI INT SA (LU) 2004-09-22 EP claimed
EP-0999199-B1 Method of producing naphthalenedicarboxylic acid MITSUBISHI GAS CHEMICAL CO (JP) 2004-03-31 EP claimed
EP-0005858-B1 PREPARATION OF POLYARYLATES UNION CARBIDE CORPORATION (US) 1983-05-11 EP claimed
JP-63311747-A None JP disclosed
JP-1154405-A None JP disclosed
EP-3323862-B1 INK JET RECORDING METHOD AND INK JET RECORDING DEVICE CANON KK (JP) 2022-06-01 EP disclosed
EP-0416376-A2 Thermoplastic polyestercarbonate-polysiloxane block-copolymers BAYER AG (DE) 1991-03-13 EP disclosed
EP-0368104-A2 Thermoplastic polyester carbonate polysiloxane block copolymers BAYER AG (DE) 1990-05-16 EP disclosed
JP-H01154405-A HEAT-RESISTING CURL CORD TOYOBO CO LTD 1989-06-16 JP disclosed
JP-S63311747-A MANUFACTURE OF IC CHIP-MOUNTING PRINTED CIRCUIT BOARD MITSUBISHI GAS CHEM CO INC 1988-12-20 JP disclosed