Sugi Predict

Sugi Predict / Compounds / SCHEMBL3739665

SCHEMBL3739665

SCHEMBL3739665

O=C(CCCCl)N1CC[N]CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 1/20 0.48
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ NPC1 O15118 2/20 0.41
▸ KMT2A Q03164 4/20 0.40
▸ MEN1 O00255 3/20 0.40
▸ TDP1 Q9NUW8 2/20 0.40
▸ HPGD P15428 5/20 0.39
▸ ALDH1A1 P00352 4/20 0.39
▸ LMNA P02545 2/20 0.39
▸ USP2 O75604 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ NPSR1 Q6W5P4 2/20 0.37
▸ RAB9A P51151 2/20 0.37
▸ HTT P42858 1/20 0.37
▸ TAAR1 Q96RJ0 1/20 0.37
▸ MAPT P10636 2/20 0.36
▸ GNAI3 P08754 2/20 0.36
▸ GNAI1 P63096 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3737914 0.88 ALDH1A1 (0.41) ATML3MBTL1NPC1KMT2AMEN1
SCHEMBL3555230 0.82 ATM (0.50) ATML3MBTL1NPC1KMT2AMEN1
SCHEMBL7300659 0.81 ATM (0.74) ATML3MBTL1NPC1KMT2AMEN1
SCHEMBL1578576 0.80 ATM (0.48) ATML3MBTL1NPC1KMT2AMEN1
SCHEMBL4684014 0.80 L3MBTL1 (0.60) ATML3MBTL1NPC1KMT2AMEN1
SCHEMBL4300046 0.79 ATM (0.71) ATML3MBTL1NPC1KMT2AMEN1
SCHEMBL3549871 0.79 ALDH1A1 (0.52) ATMKMT2AMEN1TDP1HPGD
SCHEMBL7506937 0.78 L3MBTL1 (0.69) ATML3MBTL1NPC1KMT2AMEN1
SCHEMBL1578993 0.78 ATM (0.47) ATML3MBTL1NPC1KMT2AMEN1
SCHEMBL3736530 0.77 NPC1 (0.47) ATML3MBTL1NPC1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7829567-B2 Imino-indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same KAOHSIUNG MEDICAL UNIVERSITY (TW) 2010-11-09 — — US claimed
US-20090111987-A1 Imino-Indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same KAOHSIUNG MEDICAL UNIVERSITY (TW) 2009-04-30 — — US claimed
US-7829567-B2 Imino-indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same KAOHSIUNG MEDICAL UNIVERSITY (TW) 2010-11-09 — — US disclosed
US-20090111987-A1 Imino-Indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same KAOHSIUNG MEDICAL UNIVERSITY (TW) 2009-04-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090111987-A1 Imino-Indeno[1,2-c] quinoline derivatives, their preparation processes, and pharmaceutical compositions comprising the same IMPA1, IMPDH1, IPO5 ATM 984/4885L3MBTL1 4188/4885NPC1 335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.