SCHEMBL3740131

SCHEMBL3740131

Cc1cccc(C(C)(C)c2ccccc2)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.42
ESR2 Q92731 3/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP3A4 P08684 1/20 0.42
TRPA1 O75762 1/20 0.41
ATM Q13315 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
KIF11 P52732 1/20 0.37
MAPK1 P28482 1/20 0.37
CNR1 P21554 2/20 0.37
CNR2 P34972 2/20 0.37
ACHE P22303 2/20 0.36
TSHR P16473 1/20 0.36
KCNN4 O15554 2/20 0.36
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
ALOX15 P16050 1/20 0.34
NR3C2 P08235 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27996854 0.89 ESR1 (0.35) ESR1ESR2ALDH1A1CYP3A4TRPA1
Isothiocyanate SCHEMBL28199826 0.89 ESR1 (0.35) ESR1ESR2ALDH1A1CYP3A4TRPA1
SCHEMBL9421204 0.85 ESR1 (0.46) ESR1ESR2ALDH1A1CYP3A4GABRA1
SCHEMBL9242980 0.84 LTA4H (0.40) ESR1ESR2ALDH1A1CYP3A4MAPK1
SCHEMBL9065287 0.84 TRPA1 (0.50) ALDH1A1TRPA1ATMGABRA1GABRB2
SCHEMBL7570118 0.83 TRPA1 (0.59) ESR1ESR2ALDH1A1CYP3A4TRPA1
SCHEMBL5598485 0.83 ESR1 (0.44) ESR1ESR2ALDH1A1CYP3A4TRPA1
SCHEMBL31140137 0.82 TRPA1 (0.45) ESR1ESR2ALDH1A1CYP3A4TRPA1
SCHEMBL10634183 0.82 ESR1 (0.41) ESR1ESR2ALDH1A1CYP3A4GABRA1
SCHEMBL8853833 0.80 TRPA1 (0.39) ESR1ESR2ALDH1A1CYP3A4TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108997285-B Method for synthesizing benzophenone tetracarboxylic dianhydride in continuous flow microchannel reactor 山东冠森高分子材料科技股份有限公司 2022-07-19 CN claimed
CN-108997285-A The method of benzophenone tetracarboxylic dianhydride is synthesized in continuous flow micro passage reaction 山东冠森高分子材料科技股份有限公司 2018-12-14 CN claimed
US-20100292510-A1 PROCESS FOR PREPARING CYCLOALIPHATIC AMINES BASF SE (DE) 2010-11-18 US claimed
EP-0502387-B1 Process for producing 3,3',4,4'-tetramethyldiphenylmethane MITSUBISHI GAS CHEMICAL CO (JP) 1995-04-26 EP claimed
US-5254768-A Catalytic isomerization MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1993-10-19 US claimed
US-5210353-A Transarylalkylation AMOCO CORPORATION (US) 1993-05-11 US claimed
EP-0502387-A1 Process for producing 3,3',4,4'-tetramethyldiphenylmethane MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-09-09 EP claimed
JP-4275241-A None JP disclosed
CN-120136655-A Preparation method of 3,3', 4' -tetramethyl diphenyl alkane 常州大学 2025-06-13 CN disclosed
CN-113929866-B Modified resin and resin composition 旭化成株式会社 2023-07-07 CN disclosed
CN-108997285-B Method for synthesizing benzophenone tetracarboxylic dianhydride in continuous flow microchannel reactor 山东冠森高分子材料科技股份有限公司 2022-07-19 CN disclosed
CN-108997285-B Method for synthesizing benzophenone tetracarboxylic dianhydride in continuous flow microchannel reactor 山东冠森高分子材料科技股份有限公司 2022-07-19 CN disclosed
CN-111205424-B Modified resin and resin composition 旭化成株式会社 2022-04-08 CN disclosed
US-5136114-A PROCESS FOR THE PREPARATION OF GEMINAL DIARYLALKANES, NEW GEMINAL DIARYLALKANES AND ALK(EN)YLATED AROMATIC COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1992-08-04 US disclosed
US-5081758-A Impregnation with aromatic hydrocarbon mixture NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-01-21 US disclosed
US-5017733-A Aromatic hydrocarbons NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-05-21 US disclosed
EP-0399284-A2 Method for the production of geminal diarylalkanes, geminal diarylalkanes and alk(en)ylated aromatic compounds BAYER AG (DE) 1990-11-28 EP disclosed
US-4816526-A Polyimide/polyetherimide resin blends ICI AMERICAS INC. (US) 1989-03-28 US disclosed
US-4757120-A Polyimide/aromatic sulfone resin blends and prepegs coated therewith ICI AMERICAS INC. (US) 1988-07-12 US disclosed
EP-0259798-A2 Electrical insulating oil composition NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-03-16 EP disclosed