Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3742529 | 0.77 | KCNA5 (0.49) | CYP1A2KDM4EGAA | |
| SCHEMBL26917371 | 0.75 | SLC22A12 (0.42) | TSHRSMN1; SMN2HDAC1HDAC6SLC22A12 | |
| SCHEMBL29858057 | 0.75 | SLC22A12 (0.42) | TSHRSMN1; SMN2HDAC1HDAC6SLC22A12 | |
| SCHEMBL584028 | 0.74 | CYP2C19 (0.47) | TSHRHDAC1HDAC6KMT2ACYP1A2 | |
| SCHEMBL5570579 | 0.74 | CYP2C19 (0.47) | TSHRHDAC1HDAC6KMT2ACYP1A2 | |
| SCHEMBL7899580 | 0.74 | CYP2C19 (0.47) | TSHRHDAC1HDAC6KMT2ACYP1A2 | |
| SCHEMBL7753106 | 0.74 | SLC22A12 (0.41) | TSHRSMN1; SMN2HDAC1HDAC6SLC22A12 | |
| SCHEMBL17589159 | 0.74 | HDAC1 (0.41) | TSHRSMN1; SMN2HDAC1HDAC6SLC22A12 | |
| Hydrochloric Acid SCHEMBL17583182 | 0.72 | HDAC1 (0.40) | TSHRSMN1; SMN2HDAC1HDAC6SLC22A12 | |
| Ammonia Solution, Strong SCHEMBL3396016 | 0.72 | CYP2C19 (0.45) | TSHRKMT2ACYP1A2MAPTGLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286152-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GIPR, GHSR, GLP1R | TSHR 47/4885SMN1; SMN2 3692/4885HDAC1 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.