Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 17/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3667305 | 0.90 | GHSR (0.47) | GHSRTACR1 | |
| SCHEMBL3666028 | 0.90 | GHSR (0.47) | GHSRTACR1 | |
| SCHEMBL3634488 | 0.89 | TACR1 (0.51) | GHSRTACR1 | |
| SCHEMBL3666507 | 0.87 | TACR1 (0.45) | GHSRTACR1 | |
| SCHEMBL3801373 | 0.85 | GHSR (0.50) | GHSRTACR1 | |
| SCHEMBL3666109 | 0.85 | GHSR (0.50) | GHSRTACR1 | |
| SCHEMBL3724611 | 0.82 | GHSR (0.69) | GHSRTACR1 | |
| SCHEMBL3673888 | 0.82 | GHSR (0.69) | GHSRTACR1 | |
| SCHEMBL3636170 | 0.81 | GHSR (0.42) | GHSRTACR1 | |
| SCHEMBL3639324 | 0.80 | GHSR (0.69) | GHSRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167466-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | Glaxo Group Limited (GB) | 2010-03-31 | — | — | EP | claimed |
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | claimed |
| EP-2167466-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | Glaxo Group Limited (GB) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |