Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.69 |
| ▸ | TACR1 | P25103 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724611 | 1.00 | GHSR (0.69) | GHSRTACR1CYP3A4CYP3A5CCR2 | |
| SCHEMBL3666109 | 0.83 | GHSR (0.50) | GHSRTACR1CYP3A4NPSR1CYP2D6 | |
| SCHEMBL3801373 | 0.83 | GHSR (0.50) | GHSRTACR1CYP3A4NPSR1CYP2D6 | |
| SCHEMBL3740489 | 0.82 | GHSR (0.47) | GHSRTACR1 | |
| SCHEMBL3743921 | 0.81 | GHSR (1.00) | GHSRTACR1CYP3A4CYP3A5CCR2 | |
| SCHEMBL3727187 | 0.81 | TACR1 (0.50) | GHSRTACR1CYP3A4NPSR1CYP2D6 | |
| SCHEMBL3635981 | 0.81 | GHSR (1.00) | GHSRTACR1CYP3A4CYP3A5CCR2 | |
| SCHEMBL3640133 | 0.81 | GHSR (1.00) | GHSRTACR1CYP3A4CYP3A5CCR2 | |
| SCHEMBL3741670 | 0.81 | GHSR (1.00) | GHSRTACR1CYP3A4CYP3A5CCR2 | |
| SCHEMBL3667305 | 0.81 | GHSR (0.47) | GHSRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167466-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | Glaxo Group Limited (GB) | 2010-03-31 | — | — | EP | claimed |
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | claimed |
| EP-2167466-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | Glaxo Group Limited (GB) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008148853-A1 | N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR | GLAXO GROUP LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |