Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.72 |
| ▸ | KDR | P35968 | 18/20 | 0.72 |
| ▸ | IGF1R | P08069 | 17/20 | 0.72 |
| ▸ | MST1R | Q04912 | 2/20 | 0.71 |
| ▸ | INSR | P06213 | 2/20 | 0.71 |
| ▸ | AURKA | O14965 | 1/20 | 0.71 |
| ▸ | JAK2 | O60674 | 1/20 | 0.71 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.71 |
| ▸ | ABL1 | P00519 | 1/20 | 0.71 |
| ▸ | LCK | P06239 | 1/20 | 0.71 |
| ▸ | RET | P07949 | 1/20 | 0.71 |
| ▸ | KIT | P10721 | 1/20 | 0.71 |
| ▸ | PIM1 | P11309 | 1/20 | 0.71 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.71 |
| ▸ | SRC | P12931 | 1/20 | 0.71 |
| ▸ | PRKACA | P17612 | 1/20 | 0.71 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.71 |
| ▸ | JAK1 | P23458 | 1/20 | 0.71 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.71 |
| ▸ | AKT1 | P31749 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3676677 | 1.00 | MET (0.72) | METKDRIGF1RMST1RINSR | |
| SCHEMBL11914114 | 1.00 | MET (0.72) | METKDRIGF1RMST1RINSR | |
| Hydrochloric Acid SCHEMBL374145 | 0.99 | MET (0.72) | METKDRIGF1RMST1RINSR | |
| Hydrochloric Acid SCHEMBL373747 | 0.99 | MET (0.72) | METKDRIGF1RMST1RINSR | |
| Hydrochloric Acid SCHEMBL3674902 | 0.99 | MET (0.72) | METKDRIGF1RMST1RINSR | |
| SCHEMBL373734 | 0.93 | MET (0.84) | METKDRIGF1RMST1R | |
| SCHEMBL373735 | 0.93 | MET (0.84) | METKDRIGF1RMST1R | |
| SCHEMBL373669 | 0.93 | MET (0.84) | METKDRIGF1RMST1R | |
| SCHEMBL373934 | 0.93 | MET (0.84) | METKDRIGF1RMST1R | |
| SCHEMBL3674530 | 0.93 | MET (0.84) | METKDRIGF1RMST1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408300-A1 | AMINO ESTER DERIVATIVES, SALTS THEREOF AND METHODS OF USE | Sunshine Lake Pharma Co., Ltd (CN) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010111063-A1 | AMINO ESTER DERIVATIVES, SALTS THEREOF AND METHODS OF USE | XI NING (US) | 2010-09-30 | — | — | WO | disclosed |