Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL3740922

CCCCCCCCOc1ccc(-c2cccc(OS(=O)(=O)C(F)(F)F)c2-c2ccc(OCCCCCCCC)cc2)cc1.S

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.43
FFAR4 Q5NUL3 2/20 0.42
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
PTPN11 Q06124 3/20 0.39
KCNA3 P22001 1/20 0.39
LTA4H P09960 1/20 0.39
PLA2G4B P0C869 2/20 0.39
PDK2 Q15119 1/20 0.39
PTPN1 P18031 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL1088675 0.79 DRD2 (0.43)
Trifluoromethanesulfonic Acid SCHEMBL4620193 0.78 RARB (0.45) RARBFFAR4TP53TSHRPTPN11
Trifluoromethanesulfonic Acid SCHEMBL3740925 0.78 RARB (0.45) RARBFFAR4TP53TSHRPTPN11
Trifluoromethanesulfonic Acid SCHEMBL4620136 0.78 RARB (0.45) RARBFFAR4TP53TSHRPTPN11
SCHEMBL16076556 0.78 KCNA3 (0.51) KCNA3
SCHEMBL28194312 0.77 LTA4H (0.57) RARBTP53TSHRPTPN11LTA4H
SCHEMBL12646855 0.77 KDM4E (0.42) FFAR4PTPN1
SCHEMBL30705191 0.77 DRD2 (0.44)
Iodide SCHEMBL8736416 0.77 PTGDR2 (0.47) PTPN11PLA2G4BPDK2PTPN1
SCHEMBL7110393 0.76 PDK2 (0.41) RARBTP53TSHRPTPN11LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7833693-B2 Iodonium or sulfonium di-(tetrafluoroethyl sulfonate) ether acid generators; imaging negative and positive patterns in semiconductors and photoresists; microlithography; high photosensitivity AZ ELECTRONIC MATERIALS USA CORP. 2010-11-16 US disclosed
US-7521170-B2 Photoactive compounds AZ ELECTRONIC MATERIALS USA CORP. (US) 2009-04-21 US disclosed
US-20070015084-A1 Iodonium or sulfonium di-(tetrafluoroethyl sulfonate) ether acid generators; imaging negative and positive patterns in semiconductors and photoresists; microlithography; high photosensitivity MERCK PATENT GMBH (DE) 2007-01-18 US disclosed