Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.61 |
| ▸ | ITGB6 | P18564 | 12/20 | 0.45 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411014 | 0.81 | ITGAV (0.66) | ITGAVITGB3ITGB6ITGA5 | |
| SCHEMBL274666 | 0.80 | ITGAV (0.67) | ITGAVITGB3ITGB6ITGA5 | |
| Trifluoroacetic Acid SCHEMBL275120 | 0.78 | ITGAV (0.62) | ITGAVITGB3ITGB6ITGA5 | |
| SCHEMBL6421344 | 0.77 | ITGAV (1.00) | ITGAVITGB3ITGB6 | |
| SCHEMBL6421342 | 0.77 | ITGAV (1.00) | ITGAVITGB3ITGB6 | |
| SCHEMBL276261 | 0.77 | ITGAV (0.65) | ITGAVITGB3ITGB6ITGA5 | |
| SCHEMBL276941 | 0.76 | ITGAV (0.58) | ITGAVITGB3ITGB6 | |
| SCHEMBL275899 | 0.75 | ITGAV (0.59) | ITGAVITGB3ITGB6ITGA5 | |
| SCHEMBL22029457 | 0.74 | ITGAV (0.85) | ITGAVITGB3ITGB6 | |
| SCHEMBL22029471 | 0.74 | ITGAV (0.85) | ITGAVITGB3ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825119-B2 | Bone disorders such as osteoporosis, tumors and cardiovascular disorders; 4-(2-carboxy-2-Boc-aminoethylamino)-6-piperidinopyrimidines such as tert-butyl 2-benzyloxycarbonylamino-3-[2,5-dimethoxy-6-(4-[1,8]naphthyridin-2-yl-piperidin-1-yl)pyrimidin-4-ylamino]-propionate | GALAPAGOS SAS (FR) | 2010-11-02 | — | — | US | disclosed |