⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967620 | 1.00 | — | — | |
| SCHEMBL8357828 | 1.00 | — | — | |
| SCHEMBL2707394 | 0.92 | — | — | |
| SCHEMBL95320 | 0.92 | — | — | |
| SCHEMBL3544913 | 0.90 | ALDH1A1 (0.32) | — | |
| SCHEMBL3551279 | 0.90 | ALDH1A1 (0.32) | — | |
| SCHEMBL3547678 | 0.90 | ALDH1A1 (0.32) | — | |
| SCHEMBL3540638 | 0.90 | — | — | |
| SCHEMBL3551062 | 0.90 | ALDH1A1 (0.32) | — | |
| SCHEMBL3548232 | 0.90 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2206 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3984994-B1 | SUBSTITUTED PIPERIDINE COMPOUND AS OREXIN TYPE 2 AGONIST FOR THE TREATMENT OF NARCOLEPSY | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-03 | — | — | EP | claimed |
| WO-2024114814-A1 | JAK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | ONQUALITY PHARMACEUTICALS CHINA LTD (CN) | 2024-06-06 | — | — | WO | claimed |
| CN-116675685-A | Pyridine-containing bisoxazolidone compound and synthetic method and application thereof | 东北农业大学 | 2023-09-01 | — | — | CN | claimed |
| EP-3896060-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2023-08-16 | — | — | EP | claimed |
| EP-3609883-B1 | FLUORINE-SUBSTITUTED INDAZOLE COMPOUNDS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2022-06-29 | — | — | EP | claimed |
| EP-3984994-A1 | SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2022-04-20 | — | — | EP | claimed |
| CN-114306324-A | Antitumor activity and application of rotigotine and derivatives thereof | 万宜合药业(海南)有限责任公司 | 2022-04-12 | — | — | CN | claimed |
| CN-114288299-A | Antitumor activity and application of LP-211 and derivatives thereof | 万宜合药业(海南)有限责任公司 | 2022-04-08 | — | — | CN | claimed |
| CN-114246869-A | Anti-tumor activity and application of bifeprunox and derivatives thereof | 万宜合药业(海南)有限责任公司 | 2022-03-29 | — | — | CN | claimed |
| CN-114209701-A | Antineoplastic activity and application of vortioxetine and derivative thereof | 万宜合药业(海南)有限责任公司 | 2022-03-22 | — | — | CN | claimed |
| US-5686612-A | ACCELERATORS IN THE MANUFACTURE OF RUBBER AND ACTIVATORS FOR THIAZOLE ACCELERATORS | BRANTFORD CHEMICALS INC. (CA) | 1997-11-11 | — | — | US | claimed |
| WO-1997009319-A1 | SUBSTITUTED 1-AMINO-3-PHENYLURACIL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-13 | — | — | WO | claimed |
| US-5502035-A | N-terminus modified analogs of LHRH | TAP HOLDINGS INC. (US) | 1996-03-26 | — | — | US | claimed |
| EP-0656885-A1 | SYNTHESIS OF 2-SUBSTITUTED QUINAZOLINE COMPOUNDS (SUCH AS TERAZOSIN) AND MEOBENTINE AND BETHANIDINE AND INTERMEDIATES THEREFOR | ACIC (CANADA) INC. (CA) | 1995-06-14 | — | — | EP | claimed |
| US-5312820-A | Angiotensin antagonist for treatment of hypertension | MERCK & CO., INC. (US) | 1994-05-17 | — | — | US | claimed |
| WO-1994005628-A1 | SYNTHESIS OF 2-SUBSTITUTED QUINAZOLINE COMPOUNDS (SUCH AS TERAZOSIN) AND MEOBENTINE AND BETHANIDINE AND INTERMEDIATES THEREFOR | ACIC (CANADA) INC. (CA) | 1994-03-17 | — | — | WO | claimed |
| EP-0064255-B1 | BENZOPYRANYL ETHERS, PROCESS FOR THEIR PREPARATION AND MEDICINE CONTAINING THOSE COMPOUNDS AND INTERMEDIATES | Roche Diagnostics GmbH (DE) | 1984-12-12 | — | — | EP | claimed |
| US-4428955-A | ALLERGIC DISEASES | BOEHRINGER MANNHEIM GMBH (DE) | 1984-01-31 | — | — | US | claimed |
| EP-0079545-A1 | Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same | KANEBO, LTD. (JP) | 1983-05-25 | — | — | EP | claimed |
| US-4093726-A | HYPOTENSIVE AGENTS | ABBOTT LABORATORIES (US) | 1978-06-06 | — | — | US | claimed |