⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37418 | 1.00 | — | — | |
| SCHEMBL8357828 | 1.00 | — | — | |
| SCHEMBL2707394 | 0.92 | — | — | |
| SCHEMBL95320 | 0.92 | — | — | |
| SCHEMBL3544913 | 0.90 | ALDH1A1 (0.32) | — | |
| SCHEMBL3551279 | 0.90 | ALDH1A1 (0.32) | — | |
| SCHEMBL3547678 | 0.90 | ALDH1A1 (0.32) | — | |
| SCHEMBL3540638 | 0.90 | — | — | |
| SCHEMBL3551062 | 0.90 | ALDH1A1 (0.32) | — | |
| SCHEMBL3548232 | 0.90 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008007930-A9 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD (KR) | 2009-04-02 | — | — | WO | claimed |
| US-20240166625-A1 | Substituted 4-Benzyl And 4-Benzoyl Piperidine Derivates | CEPHALON LLC | 2024-05-23 | — | — | US | disclosed |
| EP-3310773-B1 | SUBSTITUTED 4-BENZYL AND 4-BENZOYL PIPERIDINE DERIVATIVES | 89BIO LTD (IL) | 2020-12-02 | — | — | EP | disclosed |
| US-20200031797-A1 | SUBSTITUTED 4-BENZYL AND 4-BENZOYL PIPERIDINE DERIVATIVES | CEPHALON LLC | 2020-01-30 | — | — | US | disclosed |
| US-5885981-A | REACTING A HALOGENATED ALKYL COMPOUND WITH A PENEM COMPOUND | SUNTORY LIMITED (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0738154-A1 | N-TERMINUS MODIFIED ANALOGS OF LHRH | Abbott Laboratories (US) | 1996-10-23 | — | — | EP | disclosed |
| EP-0738154-A4 | N-TERMINUS MODIFIED ANALOGS OF LHRH | ABBOTT LAB (US) | 1996-04-12 | — | — | EP | disclosed |
| US-5502035-A | N-terminus modified analogs of LHRH | TAP HOLDINGS INC. (US) | 1996-03-26 | — | — | US | disclosed |
| WO-1995004541-A1 | N-TERMINUS MODIFIED ANALOGS OF LHRH | ABBOTT LABORATORIES (US) | 1995-02-16 | — | — | WO | disclosed |