Ethylene Glycol

Ethylene Glycol

SCHEMBL3741801

C=CCc1ccccc1OCCCCCCCCC.OCCO

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.53
ALDH1A1 P00352 4/20 0.53
LMNA P02545 3/20 0.48
HTR2B P41595 2/20 0.48
MEN1 O00255 1/20 0.48
NR1I2 O75469 1/20 0.48
CHRM2 P08172 1/20 0.48
CYP3A4 P08684 1/20 0.48
ADRA2A P08913 1/20 0.48
MAPT P10636 1/20 0.48
OPRK1 P41145 1/20 0.48
SLC6A3 Q01959 1/20 0.48
KMT2A Q03164 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
ADRB2 P07550 3/20 0.47
ADRB1 P08588 3/20 0.47
HTR1A P08908 1/20 0.47
ADRB3 P13945 1/20 0.47
ADRA2C P18825 1/20 0.47
SLC6A2 P23975 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL3728134 1.00 KDM4E (0.53) KDM4EALDH1A1LMNAHTR2BMEN1
SCHEMBL28158323 0.94 KDM4E (0.58) KDM4EALDH1A1LMNAHTR2BMEN1
SCHEMBL28783874 0.92 KDM4E (0.60) KDM4EALDH1A1LMNAHTR2BMAPT
SCHEMBL8072797 0.89 KDM4E (0.60) KDM4EALDH1A1LMNAHTR2BMAPT
SCHEMBL4540726 0.86 KDM4E (0.60) KDM4EALDH1A1LMNAHTR2BADRA2A
SCHEMBL9627195 0.86 KDM4E (0.67) KDM4EALDH1A1LMNAHTR2BADRA2A
SCHEMBL9626411 0.86 KDM4E (0.67) KDM4EALDH1A1LMNAHTR2BADRA2A
SCHEMBL9625662 0.86 KDM4E (0.67) KDM4EALDH1A1LMNAHTR2BADRA2A
SCHEMBL252950 0.84 KDM4E (0.57) KDM4EALDH1A1LMNAHTR2BADRA2A
SCHEMBL8077527 0.84 ALDH1A1 (0.57) KDM4EALDH1A1LMNAHTR2BADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2139932-B1 COMPOSITE PARTICLE AND PRODUCTION METHOD THEREOF CANON KK (JP) 2012-11-07 EP disclosed
EP-2139932-A1 COMPOSITE PARTICLE AND PRODUCTION METHOD THEREOF Canon Kabushiki Kaisha (JP) 2010-01-06 EP disclosed
US-20090166578-A1 COMPOSITE PARTICLE AND PRODUCTION METHOD THEREOF CANON KABUSHIKI KAISHA (JP) 2009-07-02 US disclosed
WO-2009001789-A1 COMPOSITE PARTICLE AND PRODUCTION METHOD THEREOF CANON KABUSHIKI KAISHA (JP) 2008-12-31 WO disclosed