Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | CNR2 | P34972 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28783874 | 0.97 | KDM4E (0.60) | KDM4EALDH1A1CNR2CYP1A2CYP2C9 | |
| SCHEMBL28158323 | 0.95 | KDM4E (0.58) | KDM4EALDH1A1CNR2CYP1A2ADRB2 | |
| SCHEMBL8077527 | 0.91 | ALDH1A1 (0.57) | KDM4EALDH1A1CNR2CYP1A2ADRB2 | |
| SCHEMBL9625908 | 0.91 | KDM4E (0.69) | KDM4EALDH1A1CYP1A2ADRB2ADRB1 | |
| Ethylene Glycol SCHEMBL3728134 | 0.89 | KDM4E (0.53) | KDM4EALDH1A1CNR2CYP1A2CNR1 | |
| Ethylene Glycol SCHEMBL3741801 | 0.89 | KDM4E (0.53) | KDM4EALDH1A1CNR2CYP1A2CNR1 | |
| SCHEMBL9627195 | 0.89 | KDM4E (0.67) | KDM4EALDH1A1CYP1A2ADRB2ADRB1 | |
| SCHEMBL9625662 | 0.89 | KDM4E (0.67) | KDM4EALDH1A1CYP1A2ADRB2ADRB1 | |
| SCHEMBL9626411 | 0.89 | KDM4E (0.67) | KDM4EALDH1A1CYP1A2ADRB2ADRB1 | |
| SCHEMBL9625872 | 0.89 | KDM4E (0.67) | KDM4EALDH1A1CYP1A2ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10279509-A | — | — | None | — | — | JP | disclosed |
| US-20160311792-A1 | Sulfamate Derivative Compounds for Use in Treating or Alleviating Pain | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2016-10-27 | — | — | US | disclosed |
| WO-2015088272-A9 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2015-10-01 | — | — | WO | disclosed |
| WO-2015088272-A1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2015-06-18 | — | — | WO | disclosed |
| US-6063940-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| JP-H10279509-A | PRODUCTION OF PARA-OR META-HYDROXYALKYLBENZENE AND ITS INTERMEDIATE | HOKKO CHEM IND CO LTD | 1998-10-20 | — | — | JP | disclosed |
| US-5637736-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-10 | — | — | US | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311792-A1 | Sulfamate Derivative Compounds for Use in Treating or Alleviating Pain | SULT2A1, SULT1A1, TRPV1 | KDM4E 1943/4885ALDH1A1 894/4885CNR2 155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.