Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475032 | 0.89 | HRH3 (0.49) | HRH3HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL10274867 | 0.84 | HRH3 (0.55) | HRH3HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL186721 | 0.83 | HRH3 (0.51) | HRH3HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL1295721 | 0.83 | HRH3 (0.51) | HRH3HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL28492122 | 0.83 | HRH3 (0.51) | HRH3HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL13291479 | 0.82 | HRH3 (0.54) | HRH3HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL5023573 | 0.82 | HRH3 (0.54) | HRH3HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL28055168 | 0.82 | HRH3 (0.77) | HRH3HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL374206 | 0.82 | HRH3 (0.54) | HRH3HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL310852 | 0.81 | HRH3 (0.60) | HRH3HPGDKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717602-B | Kinase inhibitors | 加利福尼亚大学董事会 | 2016-11-09 | — | — | CN | disclosed |
| WO-2015069110-A1 | MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS | AAPA B.V. (NL) | 2015-05-14 | — | — | WO | disclosed |
| CN-103717602-A | Kinase inhibitors | UNIV CALIFORNIA | 2014-04-09 | — | — | CN | disclosed |
| EP-2069312-A2 | PYRIDIZINONE DERIVATIVES | Cephalon, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008013838-A2 | PYRIDIZINONE DERIVATIVES | CEPHALON, INC. (US) | 2008-01-31 | — | — | WO | disclosed |