Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.34 |
| ▸ | MGAT2 | Q10469 | 3/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3739269 | 0.99 | MAOB (0.36) | MAOBNPC1RAB9ATLR8MGAT2 | |
| SCHEMBL3738424 | 0.86 | LTB4R (0.35) | MAOBLTB4RPDE2A | |
| SCHEMBL3741634 | 0.86 | LTB4R (0.35) | MAOBLTB4RPDE2A | |
| SCHEMBL3745793 | 0.86 | LTB4R (0.35) | MAOBLTB4RPDE2A | |
| SCHEMBL3742726 | 0.86 | MAOB (0.34) | MAOBLTB4RMEN1KMT2A | |
| SCHEMBL3735599 | 0.85 | LTB4R (0.35) | MAOBLTB4RPDE2A | |
| SCHEMBL3738043 | 0.83 | LTB4R (0.35) | MAOBLTB4RCYP3A4MAPK1CYP2C19 | |
| SCHEMBL3745630 | 0.81 | MAOB (0.37) | MAOBMGAT2LTB4RPDE2A | |
| SCHEMBL3741486 | 0.77 | LTB4R (0.34) | LTB4R | |
| SCHEMBL3732538 | 0.77 | LTB4R (0.34) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829578-B1 | Aromatic ketones and uses thereof | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |