Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3745793 | 1.00 | LTB4R (0.35) | LTB4RPDE2AMAOBSCN8ASCN10A | |
| SCHEMBL3738424 | 1.00 | LTB4R (0.35) | LTB4RPDE2AMAOBSCN8ASCN10A | |
| SCHEMBL3735599 | 0.99 | LTB4R (0.35) | LTB4RPDE2AMAOBSCN8ASCN10A | |
| SCHEMBL3745630 | 0.96 | MAOB (0.37) | LTB4RPDE2AMAOBSCN8ASCN10A | |
| SCHEMBL3732538 | 0.91 | LTB4R (0.34) | LTB4R | |
| SCHEMBL3741486 | 0.91 | LTB4R (0.34) | LTB4R | |
| SCHEMBL3742726 | 0.88 | MAOB (0.34) | LTB4RMAOB | |
| SCHEMBL3746423 | 0.87 | LTB4R (0.34) | LTB4RPDE2ACNR1 | |
| SCHEMBL3742855 | 0.86 | MAOB (0.36) | LTB4RPDE2AMAOB | |
| SCHEMBL3738043 | 0.84 | LTB4R (0.35) | LTB4RMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829578-B1 | Aromatic ketones and uses thereof | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |