Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17531044 | 0.88 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1096865 | 0.86 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1096099 | 0.84 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1564891 | 0.78 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL3748159 | 0.77 | SMN1; SMN2 (0.34) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1425193 | 0.77 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14562814 | 0.77 | — | — | |
| SCHEMBL229582 | 0.76 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL27498130 | 0.76 | SMN1; SMN2 (0.32) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL776778 | 0.75 | SLC6A2 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834120-B2 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-1645560-B1 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHINETSU CHEMICAL CO (JP) | 2008-05-28 | — | — | EP | disclosed |
| EP-1645560-A1 | Monofunctional monomer having cage oligosiloxane structure and method of making | Shin-Etsu Chemical Co., Ltd. (JP) | 2006-04-12 | — | — | EP | disclosed |
| US-20060074213-A1 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-04-06 | — | — | US | disclosed |