SCHEMBL3743489

SCHEMBL3743489

COc1ccccc1-c1cc(-c2ccccc2OC)cc(-c2ccccc2OC)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.58
PTPN1 P18031 1/20 0.58
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA4 P22748 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
ERN1 O75460 1/20 0.56
APP P05067 1/20 0.56
HTR7 P34969 3/20 0.53
PDGFRB P09619 1/20 0.53
PDGFRA P16234 1/20 0.53
ALDH1A1 P00352 4/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
HPGD P15428 1/20 0.52
KDM4E B2RXH2 3/20 0.50
CYP1A1 P04798 1/20 0.50
CYP1A2 P05177 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28102075 0.91 HTR7 (0.51) PTPRCPTPN1CA12CA1CA2
SCHEMBL28043787 0.91 HTR7 (0.51) PTPRCPTPN1CA12CA1CA2
SCHEMBL13211665 0.91 PTPRC (0.55) PTPRCPTPN1CA12CA1CA2
SCHEMBL29629017 0.91 HTR7 (0.64) PTPRCPTPN1CA12CA1CA2
SCHEMBL26556078 0.91 HTR7 (0.64) PTPRCPTPN1CA12CA1CA2
SCHEMBL294721 0.85 ALDH1A1 (0.58) PTPRCPTPN1CA12CA1CA2
SCHEMBL30136447 0.85 ALDH1A1 (0.58) PTPRCPTPN1CA12CA1CA2
SCHEMBL31199174 0.85 ERN1 (0.71) PTPRCPTPN1CA1CA2ERN1
SCHEMBL13051193 0.85 HTR7 (0.50) PTPRCPTPN1CA12CA1CA2
SCHEMBL5924656 0.85 HTR7 (0.50) PTPRCPTPN1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7833690-B2 Photoacid generators and lithographic resists comprising the same THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) 2010-11-16 US disclosed
US-20070117043-A1 Photoacid generators and lithographic resists comprising the same NATIONAL SCIENCE FOUNDATION 2007-05-24 US disclosed
US-20050175858-A1 Carbazole containing compound and organic electroluminescent display device using the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2005-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050175858-A1 Carbazole containing compound and organic electroluminescent display device using the same BRD3, BRD7, CBX7 PTPRC 978/4885PTPN1 2780/4885CA12 3693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.