⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399645 | 0.74 | ALDH1A1 (0.46) | — | |
| SCHEMBL3399641 | 0.74 | ALDH1A1 (0.46) | — | |
| SCHEMBL39387 | 0.74 | — | — | |
| SCHEMBL490224 | 0.71 | — | — | |
| SCHEMBL2877 | 0.71 | — | — | |
| SCHEMBL2546600 | 0.70 | — | — | |
| SCHEMBL42054 | 0.70 | — | — | |
| SCHEMBL73997 | 0.70 | — | — | |
| SCHEMBL17236155 | 0.70 | — | — | |
| SCHEMBL74607 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 333 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210330678-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-10-28 | — | — | US | claimed |
| EP-3897644-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. (US) | 2021-10-27 | — | — | EP | claimed |
| CN-113498342-A | Compounds involved in synergistic binding and uses thereof | 锐新医药公司 | 2021-10-12 | — | — | CN | claimed |
| EP-3846808-A2 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-07-14 | — | — | EP | claimed |
| US-20200197391-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. | 2020-06-25 | — | — | US | claimed |
| WO-2020132597-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. (US) | 2020-06-25 | — | — | WO | claimed |
| EP-3256471-B1 | NOVEL 2-OXO-6,7-DIHYDROBENZO[A]QUINOLIZINE-3-CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2018-12-12 | — | — | EP | claimed |
| US-10093671-B2 | 2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis B virus infection | HOFFMANN-LA ROCHE INC. (US) | 2018-10-09 | — | — | US | claimed |
| CN-108026432-A | Selective nitride slurry with improved stability and improved polishing characteristic | 嘉柏微电子材料股份公司 | 2018-05-11 | — | — | CN | claimed |
| US-9949966-B2 | Dihydroquinolizinones for the treatment and prophylaxis of hepatitis B virus infection | HOFFMAN-LA ROCHE INC. (US) | 2018-04-24 | — | — | US | claimed |
| US-5696194-A | CONTAINS ACRYLAMIDE, N-ALKYLACRYLAMIDE AND N,N-DIALKYLACRYLAMIDE; QUATERNIZATION | BETZDEARBORN INC. (US) | 1997-12-09 | — | — | US | claimed |
| EP-0637598-B1 | Hydrophobic dispersants used in forming polymer dispersions | NALCO CHEMICAL CO (US) | 1997-05-02 | — | — | EP | claimed |
| US-5614602-A | ADDITION POLYMERIZATION OF CATIONIC MONOMERS, USED TO DEWATER SLUDGE AND IN PAPER RETENTION | BETZDEARBORN INC. (US) | 1997-03-25 | — | — | US | claimed |
| US-5597858-A | POLYMERIZATION OF CATIONIC MONOMERS AS DISPERSANTS | NALCO CHEMICAL COMPANY (US) | 1997-01-28 | — | — | US | claimed |
| US-5597859-A | FORMING DIALKYLAMINOALKYL(METH)ACYLAMIDE POLYMER DISPERSIONS | NALCO CHEMICAL COMPANY (US) | 1997-01-28 | — | — | US | claimed |
| US-5466338-A | ADDING A WATER SOLUBLE CATIONIC POLYMER TO A REPULPED BROKE SLURRY | NALCO CHEMICAL COMPANY (US) | 1995-11-14 | — | — | US | claimed |
| EP-0657478-A2 | An improved process for the preparation of water soluble polymer dispersion | NALCO CHEMICAL COMPANY (US) | 1995-06-14 | — | — | EP | claimed |
| EP-0637598-A2 | Hydrophobic dispersants used in forming polymer dispersions | NALCO CHEMICAL COMPANY (US) | 1995-02-08 | — | — | EP | claimed |
| EP-0385630-A2 | 1H-imidazo(4,5-c)Quinolin-4-amines as antivirals | RIKER LABORATORIES, INC. (US) | 1990-09-05 | — | — | EP | claimed |
| US-4792644-A | ZEOLITE AND QUATERNARY AMMONIUM SALT | TOSOH CORPORATION (JP) | 1988-12-20 | — | — | US | claimed |