⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101405 | 0.75 | — | — | |
| SCHEMBL129819 | 0.75 | — | — | |
| SCHEMBL3400030 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL3400032 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL732006 | 0.73 | — | — | |
| SCHEMBL10405850 | 0.72 | — | — | |
| SCHEMBL5925175 | 0.70 | ALDH1A1 (0.36) | — | |
| SCHEMBL10405917 | 0.70 | — | — | |
| SCHEMBL8117204 | 0.70 | GPR84 (0.48) | — | |
| SCHEMBL8023169 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024003259-A1 | TEAD INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-01-04 | — | — | WO | claimed |
| CN-115151534-A | Inhibitors of interleukin-1 receptor-related kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2022-10-04 | — | — | CN | claimed |
| EP-3298011-B1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | PRINCIPIA BIOPHARMA INC (US) | 2021-11-17 | — | — | EP | claimed |
| CN-110465120-A | A kind of preparation method of the polyether-modified silicon defoaming agent of emulsion-type | QIDONG XIRUI NEW MATERIAL TECH CO LTD | 2019-11-19 | — | — | CN | claimed |
| EP-3154969-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2019-10-09 | — | — | EP | claimed |
| CN-109896837-A | A kind of heat-stable ceramic soup stews and preparation method thereof | 江西省康舒陶瓷有限公司 | 2019-06-18 | — | — | CN | claimed |
| US-10221197-B2 | Phosphatidylinositol 3-kinase inhibitors | GILEAD SCIENCES, INC. (US) | 2019-03-05 | — | — | US | claimed |
| EP-2976340-B1 | CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-06-13 | — | — | EP | claimed |
| US-20180155340-A1 | QUINOLONE DERIVATIVES AS FGFR INHIBITORS | PRINCIPIA BIOPHARMA INC. | 2018-06-07 | — | — | US | claimed |
| EP-3298011-A1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | PRINCIPIA BIOPHARMA INC. (US) | 2018-03-28 | — | — | EP | claimed |
| EP-0637598-B1 | Hydrophobic dispersants used in forming polymer dispersions | NALCO CHEMICAL CO (US) | 1997-05-02 | — | — | EP | claimed |
| US-5614602-A | ADDITION POLYMERIZATION OF CATIONIC MONOMERS, USED TO DEWATER SLUDGE AND IN PAPER RETENTION | BETZDEARBORN INC. (US) | 1997-03-25 | — | — | US | claimed |
| US-5597858-A | POLYMERIZATION OF CATIONIC MONOMERS AS DISPERSANTS | NALCO CHEMICAL COMPANY (US) | 1997-01-28 | — | — | US | claimed |
| US-5597859-A | FORMING DIALKYLAMINOALKYL(METH)ACYLAMIDE POLYMER DISPERSIONS | NALCO CHEMICAL COMPANY (US) | 1997-01-28 | — | — | US | claimed |
| US-5466338-A | ADDING A WATER SOLUBLE CATIONIC POLYMER TO A REPULPED BROKE SLURRY | NALCO CHEMICAL COMPANY (US) | 1995-11-14 | — | — | US | claimed |
| EP-0657478-A2 | An improved process for the preparation of water soluble polymer dispersion | NALCO CHEMICAL COMPANY (US) | 1995-06-14 | — | — | EP | claimed |
| EP-0637598-A2 | Hydrophobic dispersants used in forming polymer dispersions | NALCO CHEMICAL COMPANY (US) | 1995-02-08 | — | — | EP | claimed |
| EP-0088938-B1 | USE OF PYRIDINE COMPOUNDS FOR THE MANUFACTURE OF MEDICAMENTS WITH AN ANTIHYPOXEMIA AND ISCHEMIA-PROTECTIVE ACTIVITY | BAYER AG (DE) | 1986-04-30 | — | — | EP | claimed |
| US-4381416-A | Process for producing isoprene | KURARAY CO., LTD. (JP) | 1983-04-26 | — | — | US | claimed |
| EP-0030109-A1 | Process for producing isoprene | KURARAY CO., LTD. (JP) | 1981-06-10 | — | — | EP | claimed |