Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091737 | 0.81 | ALDH1A1 (0.40) | NPC1ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL11461967 | 0.80 | TSHR (0.43) | ALDH1A1MAPTMEN1MAPK1KMT2A | |
| SCHEMBL11547021 | 0.79 | CA5A (0.39) | NPC1ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL2094463 | 0.79 | ALDH1A1 (0.47) | NPC1ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL9837096 | 0.79 | ALDH1A1 (0.47) | NPC1ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL2094466 | 0.79 | ALDH1A1 (0.51) | NPC1ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL11426891 | 0.78 | NPC1 (0.41) | NPC1ALDH1A1MAPTMAPK1CA1 | |
| SCHEMBL28513984 | 0.78 | NT5E (0.44) | NPC1RAB9APOLBL3MBTL1CA12 | |
| SCHEMBL4303962 | 0.78 | CA12 (0.42) | NPC1ALDH1A1RAB9AMAPTMEN1 | |
| SCHEMBL11883596 | 0.77 | ALDH1A1 (0.39) | NPC1ALDH1A1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850123-B | Preparation method of 2, 4-dichloroaniline/hydrazine | 山东潍坊润丰化工股份有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-115850123-A | Preparation method of 2, 4-dichloroaniline/hydrazine | 山东潍坊润丰化工股份有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-107922326-A | The Preparation Method And Their Intermediate of Apremilast | 雷迪博士实验室有限公司 | 2018-04-17 | — | — | CN | claimed |
| WO-2014053709-A1 | A METHOD FOR CULTURING STEM CELLS | GLYKOS FINLAND OY (FI) | 2014-04-10 | — | — | WO | claimed |
| EP-2408903-A1 | CULTURE OF PLURIPOTENT AND MULTIPOTENT CELLS ON MICROCARRIERS | Agency For Science, Technology And Research (SG) | 2012-01-25 | — | — | EP | claimed |
| WO-2010107392-A1 | CULTURE OF PLURIPOTENT AND MULTIPOTENT CELLS ON MICROCARRIERS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-09-23 | — | — | WO | claimed |
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | claimed |
| CN-115850123-B | Preparation method of 2, 4-dichloroaniline/hydrazine | 山东潍坊润丰化工股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| EP-4337675-A1 | ANGIOTENSIN-(1-9) ANALOGUE BASED ON D AMINO ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Universidad De Chile (CL) | 2024-03-20 | — | — | EP | disclosed |
| CN-115850123-A | Preparation method of 2, 4-dichloroaniline/hydrazine | 山东潍坊润丰化工股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-107922326-A | The Preparation Method And Their Intermediate of Apremilast | 雷迪博士实验室有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-107614678-A | Methods for producing β cells derived from stem cells and methods of use thereof | 哈佛学院校长同事会 | 2018-01-19 | — | — | CN | disclosed |
| CN-107075469-A | Mammal limbal stem cell, its production method and its purposes of culture | 加利福尼亚大学董事会 | 2017-08-18 | — | — | CN | disclosed |
| EP-1737830-A1 | TRI-SUBSTITUTED UREAS AS CYTOKINE INHIBITORS | The Procter and Gamble Company (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005105757-A1 | TRI-SUBSTITUTED UREAS AS CYTOKINE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2005-11-10 | — | — | WO | disclosed |
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | TAISHO PHARMACEUTICAL CO., LTD. | 2005-09-08 | — | — | US | disclosed |
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |
| EP-0438209-B1 | Uracil derivatives and pesticides containing the same as active ingredient | NISSAN CHEMICAL IND LTD (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5116404-A | URACIL DERIVATIVES AND PESTICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0438209-A1 | Uracil derivatives and pesticides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1991-07-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | HCRTR2, MCHR1, MCHR2 | NPC1 778/4885ALDH1A1 2036/4885RAB9A 1648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.