Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | ILK | Q13418 | 2/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL2455715 | 0.84 | ALDH1A1 (0.44) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL8051642 | 0.82 | MAPT (0.45) | MEN1KMT2AMAPTALDH1A1PDE10A | |
| SCHEMBL9363650 | 0.82 | ASH1L (0.33) | MAPTTP53SMN1; SMN2 | |
| SCHEMBL7555956 | 0.82 | MAPT (0.39) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL9084433 | 0.82 | ALDH1A1 (0.43) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL73948 | 0.82 | MAPT (0.36) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL4031502 | 0.81 | GAA (0.44) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL17701156 | 0.81 | MAPT (0.35) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL32672712 | 0.81 | ALDH1A1 (0.36) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL32672814 | 0.81 | ALDH1A1 (0.36) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190928-A | Benzo-1,2,3-thiadiazoles | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | claimed |
| EP-0313512-B1 | BENZOTHIADIAZOLES AND THEIR USE IN PROCESSES AND COMPOSITIONS AGAINST PLANT DISEASES | CIBA-GEIGY AG (CH) | 1992-11-25 | — | — | EP | claimed |
| EP-0332104-A2 | Chemically regulatable DNA sequences and genes and uses thereof | CIBA-GEIGY AG (CH) | 1989-09-13 | — | — | EP | claimed |
| EP-0313512-A2 | Benzothiadiazoles and their use in processes and compositions against plant diseases | CIBA-GEIGY AG (CH) | 1989-04-26 | — | — | EP | claimed |
| US-8481810-B2 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATIONS AG (CH) | 2013-07-09 | — | — | US | disclosed |
| US-7838732-B2 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATIONS AG (CH) | 2010-11-23 | — | — | US | disclosed |
| WO-2009095098-A2 | USE OF BENZOTHIADIAZOLES | RWTH AACHEN (DE) | 2009-08-06 | — | — | WO | disclosed |
| US-7361806-B2 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATIONS AG (CH) | 2008-04-22 | — | — | US | disclosed |
| US-20080078005-A1 | TRANSGENIC PLANTS EXPRESSING A CELLULASE | LEBEL EDOUARD G | 2008-03-27 | — | — | US | disclosed |
| US-20080022425-A1 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATION AG | 2008-01-24 | — | — | US | disclosed |
| US-7030294-B2 | Heterologous expression cassette of a nucleotide sequence under control of an inducible promoter | SYNGENTA PARTICIPATIONS AG (CH) | 2006-04-18 | — | — | US | disclosed |
| EP-1574580-A2 | Transgenic plants expressing cellulolytic enzymes | Syngenta Participations AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| US-5304652-A | Benzo-1,2,3-thiadiazole derivatives; fungicides | CIBA-GEIGY CORPORATION (US) | 1994-04-19 | — | — | US | disclosed |
| US-5229384-A | Microbiocides | CIBA-GEIGY CORPORATION (US) | 1993-07-20 | — | — | US | disclosed |
| US-5190928-A | Benzo-1,2,3-thiadiazoles | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| EP-0313512-B1 | BENZOTHIADIAZOLES AND THEIR USE IN PROCESSES AND COMPOSITIONS AGAINST PLANT DISEASES | CIBA-GEIGY AG (CH) | 1992-11-25 | — | — | EP | disclosed |
| US-5051436-A | Heterocyclic substituted benzothiadiazoles as viricides, fungicides and bactericides | CIBA-GEIGY CORPORATION (US) | 1991-09-24 | — | — | US | disclosed |
| US-4931581-A | CHEMICAL INTERMEDIATES FOR 1,2,3-BENZOTHIADIAZOLE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0332104-A2 | Chemically regulatable DNA sequences and genes and uses thereof | CIBA-GEIGY AG (CH) | 1989-09-13 | — | — | EP | disclosed |
| EP-0313512-A2 | Benzothiadiazoles and their use in processes and compositions against plant diseases | CIBA-GEIGY AG (CH) | 1989-04-26 | — | — | EP | disclosed |