Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971403 | 0.84 | THRB (0.51) | GAAKDM4EALDH1A1MAPTTP53 | |
| SCHEMBL6971401 | 0.84 | MAPT (0.39) | ALDH1A1MAPTTP53SMN1; SMN2THRB | |
| SCHEMBL7555956 | 0.81 | MAPT (0.39) | KDM4EALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL3743974 | 0.81 | PARP1 (0.40) | GAAKDM4EALDH1A1MAPTTP53 | |
| SCHEMBL9087580 | 0.80 | LMNA (0.51) | KDM4EALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL9385271 | 0.80 | EGLN1 (0.42) | ALDH1A1MAPTTP53SMN1; SMN2THRB | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL2455715 | 0.80 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL8051642 | 0.78 | MAPT (0.45) | ALDH1A1MAPTTP53SMN1; SMN2THRB | |
| SCHEMBL73948 | 0.78 | MAPT (0.36) | GAAKDM4EALDH1A1MAPTTP53 | |
| SCHEMBL9087330 | 0.78 | GAA (0.49) | GAAKDM4EALDH1A1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332104-A2 | Chemically regulatable DNA sequences and genes and uses thereof | CIBA-GEIGY AG (CH) | 1989-09-13 | — | — | EP | claimed |
| US-8481810-B2 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATIONS AG (CH) | 2013-07-09 | — | — | US | disclosed |
| WO-2009095098-A2 | USE OF BENZOTHIADIAZOLES | RWTH AACHEN (DE) | 2009-08-06 | — | — | WO | disclosed |
| US-7361806-B2 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATIONS AG (CH) | 2008-04-22 | — | — | US | disclosed |
| US-20080022425-A1 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATION AG | 2008-01-24 | — | — | US | disclosed |
| US-7030294-B2 | Heterologous expression cassette of a nucleotide sequence under control of an inducible promoter | SYNGENTA PARTICIPATIONS AG (CH) | 2006-04-18 | — | — | US | disclosed |
| EP-1574580-A2 | Transgenic plants expressing cellulolytic enzymes | Syngenta Participations AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| EP-0925362-B1 | TRANSGENIC PLANTS EXPRESSING CELLULOLYTIC ENZYMES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-07-20 | — | — | EP | disclosed |
| CN-1552849-A | Transgenic plants expressing cellulolytic enzymes | �����ɷ� | 2004-12-08 | — | — | CN | disclosed |
| US-20040103453-A1 | Lipoxygenase genes, promoters, transit peptides and proteins thereof | SYNGENTA PARTICIPATIONS AG (CH) | 2004-05-27 | — | — | US | disclosed |
| WO-1998011235-A2 | TRANSGENIC PLANTS EXPRESSING CELLULOLYTIC ENZYMES | NOVARTIS AG (CH) | 1998-03-19 | — | — | WO | disclosed |
| WO-1998003536-A1 | CHEMICALLY-INDUCIBLE ARABIDOPSIS PR-1 PROMOTER | NOVARTIS AG (CH) | 1998-01-29 | — | — | WO | disclosed |
| US-5689044-A | GENETIC ENGINEERING | NOVARTIS CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |
| US-5654414-A | GENETIC ENGINEERING | NOVARTIS FINANCE CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |
| US-5650505-A | Chemically regulatable and anti-pathogenic DNA sequences and uses thereof | NOVARTIS CORPORATION (US) | 1997-07-22 | — | — | US | disclosed |
| US-5614395-A | SCREENING FOR AGROCHEMICALS HAVING THE ABILITY TO INDUCE SYSTEMIC ACQUIRED RESISTANCE IN PLANTS | CIBA-GEIGY CORPORATION (US) | 1997-03-25 | — | — | US | disclosed |
| US-5523311-A | CARBONYLOXY OR THIOCARBONYL-BENZO-1,2,3-THIADIAZOLE DERIVATIVES USED AS CHEMICAL ACTIVATOR TO STIMULATE PLANTS CAPACITY TO DEFEND ITSELF AGAINST MICROBIAL INFECTIONS | CIBA-GEIGY CORPORATION (US) | 1996-06-04 | — | — | US | disclosed |
| US-5190928-A | Benzo-1,2,3-thiadiazoles | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| US-4931581-A | CHEMICAL INTERMEDIATES FOR 1,2,3-BENZOTHIADIAZOLE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0332104-A2 | Chemically regulatable DNA sequences and genes and uses thereof | CIBA-GEIGY AG (CH) | 1989-09-13 | — | — | EP | disclosed |