SCHEMBL3744202

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13048243	0.90	DYRK1A (0.41)	DYRK1APIK3CGLCKABL1CYP17A1
	SCHEMBL30617081	0.90	DYRK1A (0.41)	DYRK1APIK3CGLCKABL1CYP17A1
	SCHEMBL13074537	0.90	DYRK1A (0.41)	DYRK1APIK3CGLCKPIM1ABL1
	SCHEMBL13048201	0.89	DYRK1A (0.40)	DYRK1APIK3CGLCKPIM1CLK1
	SCHEMBL289332	0.89	DYRK1A (0.42)	DYRK1APIK3CGLCKPIM1ABL1
	SCHEMBL15047268	0.83	DYRK1A (0.34)	DYRK1APIK3CGPIM1CLK1CLK2
	SCHEMBL13048773	0.83	CYP1A2 (0.48)	—
	SCHEMBL290706	0.80	SYK (0.39)	DYRK1APIK3CGLCKABL1CYP17A1
	SCHEMBL13075078	0.80	DYRK1A (0.47)	DYRK1APIK3CGPIM1CLK1CLK2
	SCHEMBL299904	0.78	LCK (0.42)	DYRK1APIK3CGLCKCYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.