SCHEMBL3744513

SCHEMBL3744513

O=P(O)(O)OP(=O)(O)OC[C@@H](O)[C@H](O)CO

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PGD P52209 3/20 0.41
MPI P34949 1/20 0.41
BTN3A1 O00481 3/20 0.41
LPAR1 Q92633 1/20 0.36
LPAR3 Q9UBY5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9577589 0.96 PGD (0.39) PGDMPIBTN3A1LPAR1LPAR3
SCHEMBL3745928 0.96 PGD (0.39) PGDMPIBTN3A1LPAR1LPAR3
SCHEMBL891922 0.89 PGD (0.39) PGDMPIBTN3A1
SCHEMBL5454027 0.89 LMNA (0.41) PGDMPIBTN3A1
SCHEMBL9577691 0.85 PGD (0.37) PGDMPIBTN3A1
SCHEMBL1160489 0.85 LMNA (0.38) PGDMPIBTN3A1
SCHEMBL14941155 0.83 PGD (0.57) PGDMPI
E968 SCHEMBL18341349 0.83 PGD (0.57) PGDMPI
SCHEMBL18341438 0.83 PGD (0.57) PGDMPI
E968 SCHEMBL18341348 0.83 PGD (0.57) PGDMPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8236784-B2 Composition comprising threitol phosphate and salts thereof SUNNY BIODISCOVERY, INC. (US) 2012-08-07 US claimed
US-20100291185-A1 THERITOL PHOSPHATES, SALTS THEREOF AND METHODS OF USE SUNNY BIODISCOVERY, INC. (US) 2010-11-18 US claimed
WO-2008144352-A1 THREITOL PHOSPHATES, SALTS THEREOF AND METHODS OF USE SUNNY BIODISCOVERY, INC. (US) 2008-11-27 WO claimed
US-8236784-B2 Composition comprising threitol phosphate and salts thereof SUNNY BIODISCOVERY, INC. (US) 2012-08-07 US disclosed
US-8236784-B2 Composition comprising threitol phosphate and salts thereof SUNNY BIODISCOVERY, INC. (US) 2012-08-07 US disclosed
US-20100291185-A1 THERITOL PHOSPHATES, SALTS THEREOF AND METHODS OF USE SUNNY BIODISCOVERY, INC. (US) 2010-11-18 US disclosed
US-20100291185-A1 THERITOL PHOSPHATES, SALTS THEREOF AND METHODS OF USE SUNNY BIODISCOVERY, INC. (US) 2010-11-18 US disclosed
WO-2008144352-A1 THREITOL PHOSPHATES, SALTS THEREOF AND METHODS OF USE SUNNY BIODISCOVERY, INC. (US) 2008-11-27 WO disclosed
WO-2008144352-A1 THREITOL PHOSPHATES, SALTS THEREOF AND METHODS OF USE SUNNY BIODISCOVERY, INC. (US) 2008-11-27 WO disclosed