Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.55 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3740569 | 0.87 | ALDH1A1 (0.59) | TSHRMCHR1LTA4HHRH3SMN1; SMN2 | |
| SCHEMBL14233388 | 0.79 | TSHR (0.64) | TSHRMCHR1LTA4HSMN1; SMN2CYP1A2 | |
| SCHEMBL9912418 | 0.79 | SMN1; SMN2 (0.74) | TSHRLTA4HSMN1; SMN2L3MBTL1CACNA1F | |
| SCHEMBL227297 | 0.78 | HRH3 (0.85) | LTA4HHRH3SCN7AHRH2HRH1 | |
| SCHEMBL2329109 | 0.77 | ALDH1A1 (0.67) | TSHRLTA4HSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL1024536 | 0.77 | TSHR (0.61) | TSHRMCHR1LTA4HSMN1; SMN2CYP1A2 | |
| SCHEMBL19582199 | 0.77 | TSHR (0.61) | TSHRMCHR1LTA4HSMN1; SMN2CYP1A2 | |
| SCHEMBL12726118 | 0.77 | SMN1; SMN2 (0.71) | TSHRLTA4HSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL4874490 | 0.76 | HRH3 (0.82) | LTA4HHRH3HRH2HRH1PTGS2 | |
| SCHEMBL10728257 | 0.76 | MRGPRX4 (0.49) | TSHRSMN1; SMN2CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834039-B2 | Oxadiazole compounds | ABBOTT LABORATORIES (US) | 2010-11-16 | — | — | US | disclosed |
| US-20080280876-A1 | Novel oxadiazole compounds | ABBVIE INC. | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280876-A1 | Novel oxadiazole compounds | S1PR3, S1PR1, S1PR2 | TSHR 1235/4885MCHR1 899/4885LTA4H 514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.