Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.54 |
| ▸ | PGR | P06401 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.50 |
| ▸ | BLM | P54132 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.50 |
| ▸ | SNCA | P37840 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3746811 | 0.88 | SHBG (0.53) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL3753713 | 0.84 | SHBG (0.48) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL3744652 | 0.83 | SHBG (0.58) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL3746531 | 0.82 | SHBG (0.57) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL3754138 | 0.82 | SHBG (0.57) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL3747284 | 0.80 | CYP17A1 (0.54) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL3746809 | 0.78 | SHBG (0.54) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL3758865 | 0.77 | SHBG (0.53) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL3744059 | 0.75 | SHBG (0.68) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL3744063 | 0.75 | SHBG (0.68) | SHBGALDH1A1NR3C1PGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292184-A1 | 17BETA-CYANO-19-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE | BAYER SCHERING PHARMA AG (DE) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292184-A1 | 17BETA-CYANO-19-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE | HSD17B11, HSD17B7, NR5A1 | SHBG 24/4885ALDH1A1 1039/4885NR3C1 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.