Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 11/20 | 0.71 |
| ▸ | MAPK9 | P45984 | 10/20 | 0.71 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3751266 | 0.86 | MAPK10 (0.74) | MAPK10MAPK9MAPK8RAB9ANPC1 | |
| Bentamapimod SCHEMBL30197744 | 0.83 | MAPK10 (1.00) | MAPK10MAPK9MAPK8RAB9ANPC1 | |
| Bentamapimod SCHEMBL2878382 | 0.83 | MAPK10 (1.00) | MAPK10MAPK9MAPK8RAB9ANPC1 | |
| Bentamapimod SCHEMBL29423429 | 0.83 | MAPK10 (1.00) | MAPK10MAPK9MAPK8RAB9ANPC1 | |
| Bentamapimod SCHEMBL29350260 | 0.83 | MAPK10 (1.00) | MAPK10MAPK9MAPK8RAB9ANPC1 | |
| SCHEMBL3747858 | 0.83 | MAPK10 (0.86) | MAPK10MAPK9MAPK8RAB9ASMN1; SMN2 | |
| SCHEMBL2883226 | 0.81 | MAPK10 (0.83) | MAPK10MAPK9MAPK8RAB9ANPC1 | |
| Bentamapimod SCHEMBL4948513 | 0.80 | MAPK10 (0.89) | MAPK10MAPK9MAPK8RAB9ANPC1 | |
| SCHEMBL2881240 | 0.79 | MAPK10 (0.88) | MAPK10MAPK9MAPK8RAB9ANPC1 | |
| SCHEMBL1518907 | 0.79 | MAPK10 (1.00) | MAPK10MAPK9MAPK8RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838522-B2 | Benzothiazole formulations and use thereof | ARES TRADING S.A. (CH) | 2010-11-23 | — | — | US | disclosed |
| US-7838522-B2 | Benzothiazole formulations and use thereof | ARES TRADING S.A. (CH) | 2010-11-23 | — | — | US | disclosed |
| US-7838522-B2 | Benzothiazole formulations and use thereof | ARES TRADING S.A. (CH) | 2010-11-23 | — | — | US | disclosed |
| US-20080051397-A1 | Benzothiazole Formulations and Use Thereof | ARES TRADING S.A. (CH) | 2008-02-28 | — | — | US | disclosed |
| US-20080051397-A1 | Benzothiazole Formulations and Use Thereof | ARES TRADING S.A. (CH) | 2008-02-28 | — | — | US | disclosed |
| US-20080051397-A1 | Benzothiazole Formulations and Use Thereof | ARES TRADING S.A. (CH) | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051397-A1 | Benzothiazole Formulations and Use Thereof | MGLL, MBOAT4, MBOAT1 | MAPK10 3176/4885MAPK9 3960/4885MAPK8 4361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.