SCHEMBL3745488

SCHEMBL3745488

CC=CCOCC1COC1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
ALDH1A1 P00352 1/20 0.32
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1478143 0.82 PTGS1 (0.33) ALDH1A1
SCHEMBL2919638 0.77
SCHEMBL159509 0.77
SCHEMBL9647153 0.75 SIGMAR1 (0.42) HTR2AHTR2CHTR2BSIGMAR1
SCHEMBL9648177 0.75 SIGMAR1 (0.42) HTR2AHTR2CHTR2BSIGMAR1
SCHEMBL9648166 0.75 SIGMAR1 (0.42) HTR2AHTR2CHTR2BSIGMAR1
SCHEMBL9647159 0.75 SIGMAR1 (0.42) HTR2AHTR2CHTR2BSIGMAR1
SCHEMBL3741994 0.74
SCHEMBL5548048 0.74 TSHR (0.32)
SCHEMBL9839222 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838626-B2 Polycarbosilane and method for producing same TOAGOSEI CO., LTD. (JP) 2010-11-23 US disclosed
US-20090163690-A1 POLYCARBOSILANE AND METHOD FOR PRODUCING SAME TOAGOSEI CO., LTD. (JP) 2009-06-25 US disclosed
EP-1867674-A1 POLYCARBOSILANE AND METHOD FOR PRODUCING SAME TOAGOSEI CO., LTD. (JP) 2007-12-19 EP disclosed