Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR2B | P41595 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647159 | 1.00 | SIGMAR1 (0.42) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL9646625 | 0.93 | HTR2A (0.39) | SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL9647863 | 0.93 | HTR2A (0.39) | SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL9647858 | 0.93 | HTR2A (0.39) | SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL9646617 | 0.93 | HTR2A (0.39) | SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL9647248 | 0.91 | ALDH1A1 (0.39) | SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL9647254 | 0.91 | ALDH1A1 (0.39) | SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL9648177 | 0.88 | SIGMAR1 (0.42) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL9648166 | 0.88 | SIGMAR1 (0.42) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL9647234 | 0.87 | HTR2A (0.38) | SIGMAR1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102578-A | Electrooptics | HOFFMANN-LA ROCHE INC. (US) | 1992-04-07 | — | — | US | disclosed |