⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1219977 | 0.93 | L3MBTL1 (0.46) | — | |
| SCHEMBL1935110 | 0.91 | L3MBTL1 (0.49) | — | |
| SCHEMBL2323038 | 0.87 | PIK3CD (0.47) | — | |
| SCHEMBL261644 | 0.85 | PIK3CD (0.58) | — | |
| SCHEMBL510427 | 0.81 | — | — | |
| SCHEMBL5424673 | 0.81 | PIK3CD (0.54) | — | |
| SCHEMBL3762707 | 0.81 | L3MBTL1 (0.43) | — | |
| SCHEMBL9730913 | 0.79 | L3MBTL1 (0.46) | — | |
| SCHEMBL19514132 | 0.79 | PIK3CD (0.52) | — | |
| SCHEMBL729385 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1055 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217764-A1 | NOX INHIBITORS FOR USE IN THE TREATMENT OF ALPORT SYNDROME | CALLIDITAS THERAPEUTICS SUISSE SA (CH) | 2023-11-16 | — | — | WO | claimed |
| CN-112457670-B | Hydrophobic polyphenylene sulfide composition with high CTI (comparative tracking index) as well as preparation method and application thereof | 金发科技股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-110982281-B | Blended fluorosilicone rubber composition and preparation method thereof | 福建拓烯新材料科技有限公司 | 2022-03-11 | — | — | CN | claimed |
| US-20210330678-A1 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-10-28 | — | — | US | claimed |
| EP-3846808-A2 | PAPD5 INHIBITORS AND METHODS OF USE THEREOF | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-07-14 | — | — | EP | claimed |
| US-20210177811-A1 | USE OF NOX INHIBITORS FOR TREATMENT OF CANCER | CALLIDITAS THERAPEUTICS SUISSE SA (CH) | 2021-06-17 | — | — | US | claimed |
| EP-3703747-A1 | USE OF NOX INHIBITORS FOR TREATMENT OF CANCER | GenKyoTex Suisse SA (CH) | 2020-09-09 | — | — | EP | claimed |
| CN-111344013-A | Use of NOX inhibitors for the treatment of cancer | 吉恩基奥泰克斯瑞士股份有限公司 | 2020-06-26 | — | — | CN | claimed |
| CN-110982281-A | Blended fluorosilicone rubber composition and preparation method thereof | 福建拓烯新材料科技有限公司 | 2020-04-10 | — | — | CN | claimed |
| EP-3479843-A1 | USE OF NOX INHIBITORS FOR TREATMENT OF CANCER | GenKyoTex Suisse SA (CH) | 2019-05-08 | — | — | EP | claimed |
| EP-0274259-B1 | New renin-inhibitory oligopeptides, their preparaton and their use | SANKYO CO (JP) | 1994-02-16 | — | — | EP | claimed |
| WO-1994002447-A1 | HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1994-02-03 | — | — | WO | claimed |
| WO-1994002446-A1 | NATURAL AMINO ACID DERIVATIVES AS METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1994-02-03 | — | — | WO | claimed |
| US-5061725-A | COGNITION ACTIVATORS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1991-10-29 | — | — | US | claimed |
| EP-0225866-B1 | QUINAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | Gerot-Pharmazeutika Gesellschaft m.b.H. (AT) | 1991-09-25 | — | — | EP | claimed |
| EP-0408524-A1 | (Pyrrolidin-2-on-l-yl) acetamides as enhancers of learning and memory and pharmaceutical compositions comprising same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1991-01-16 | — | — | EP | claimed |
| US-4818754-A | ANTIALLERGENS | BEECHAM GROUP P.L.C. OF BEECHAM HOUSE (GB) | 1989-04-04 | — | — | US | claimed |
| EP-0274259-A2 | New renin-inhibitory oligopeptides, their preparaton and their use | Sankyo Company Limited (JP) | 1988-07-13 | — | — | EP | claimed |
| EP-0243055-A2 | Pyrazolopyridine derivatives, process for their preparation, and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-10-28 | — | — | EP | claimed |
| EP-0230242-A2 | Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-29 | — | — | EP | claimed |