Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730913 | 0.98 | L3MBTL1 (0.46) | L3MBTL1CYP1A2CHRM2CHRM4CHRM5 | |
| SCHEMBL2323038 | 0.94 | PIK3CD (0.47) | CYP1A2CHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL1219977 | 0.88 | L3MBTL1 (0.46) | L3MBTL1CYP1A2CHRM2CHRM4CHRM5 | |
| SCHEMBL1935110 | 0.86 | L3MBTL1 (0.49) | L3MBTL1CYP1A2CHRM2CHRM4CHRM5 | |
| SCHEMBL1446682 | 0.82 | L3MBTL1 (0.44) | L3MBTL1CYP1A2CHRM2CHRM4CHRM5 | |
| SCHEMBL374573 | 0.81 | — | — | |
| SCHEMBL5424673 | 0.81 | PIK3CD (0.54) | CYP1A2CHRM2CHRM4CHRM5CYP2D6 | |
| SCHEMBL1447142 | 0.80 | L3MBTL1 (0.43) | L3MBTL1CYP1A2CHRM2CHRM4CHRM5 | |
| SCHEMBL1447146 | 0.80 | TSHR (0.44) | L3MBTL1CYP1A2CHRM2CHRM4CHRM5 | |
| SCHEMBL1446683 | 0.80 | KMT2A (0.45) | L3MBTL1CYP1A2CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713465-A4 | COMPOUNDS AND COMPOSITIONS AS LXR MODULATORS | IRM LLC (BM) | 2009-04-22 | — | — | EP | claimed |
| US-20070293547-A1 | Compounds and Compositions as Lxr Modulators | IRM LLC (BM) | 2007-12-20 | — | — | US | claimed |
| EP-1713465-A2 | COMPOUNDS AND COMPOSITIONS AS LXR MODULATORS | IRM LLC (BM) | 2006-10-25 | — | — | EP | claimed |
| WO-2005077122-A2 | COMPOUNDS AND COMPOSITIONS AS LXR MODULATORS | IRM LLC (BM) | 2005-08-25 | — | — | WO | claimed |
| US-11591426-B2 | Copolymer, wetting agent, medical device, and method for producing same | TORAY INDUSTRIES, INC. (JP) | 2023-02-28 | — | — | US | disclosed |
| EP-3438144-B1 | COPOLYMER, WETTING AGENT, MEDICAL DEVICE, AND METHOD FOR PRODUCING SAME | TORAY INDUSTRIES (JP) | 2021-06-30 | — | — | EP | disclosed |
| US-20210015960-A1 | COPOLYMER, WETTING AGENT, MEDICAL DEVICE, AND METHOD FOR PRODUCING SAME | TORAY INDUSTRIES, INC. (JP) | 2021-01-21 | — | — | US | disclosed |
| US-20190099511-A1 | COPOLYMER, WETTING AGENT, MEDICAL DEVICE, AND METHOD FOR PRODUCING SAME | TORAY INDUSTRIES, INC. (JP) | 2019-04-04 | — | — | US | disclosed |
| EP-3438144-A1 | COPOLYMER, WETTING AGENT, MEDICAL DEVICE, AND METHOD FOR PRODUCING SAME | Toray Industries, Inc. (JP) | 2019-02-06 | — | — | EP | disclosed |
| US-7846949-B2 | liver X receptors (LXR) modulators such as Tert-butyl 2-(2,4,6-trifluoro-N-(3-hydroxyphenyl benzamido)acetate, useful in the treatment of LXR-associated diseases such as cardiovascular disorders, inflammation and disorders of glucose metabolism such as insulin resistance and obesity | IRM LLC (BM) | 2010-12-07 | — | — | US | disclosed |
| EP-1713465-A4 | COMPOUNDS AND COMPOSITIONS AS LXR MODULATORS | IRM LLC (BM) | 2009-04-22 | — | — | EP | disclosed |
| US-20070293547-A1 | Compounds and Compositions as Lxr Modulators | IRM LLC (BM) | 2007-12-20 | — | — | US | disclosed |
| EP-1713465-A2 | COMPOUNDS AND COMPOSITIONS AS LXR MODULATORS | IRM LLC (BM) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005077122-A2 | COMPOUNDS AND COMPOSITIONS AS LXR MODULATORS | IRM LLC (BM) | 2005-08-25 | — | — | WO | disclosed |
| US-6444677-B2 | TREATMENT OF INFLAMMATION, CARDIOVASCULAR DISEASE, PAIN, ETC. | PFIZER INC. | 2002-09-03 | — | — | US | disclosed |
| EP-1106614-A1 | 5-Membered heteroaryl substituted 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER INC. (US) | 2001-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293547-A1 | Compounds and Compositions as Lxr Modulators | NR1H2, NR1H3, NR1H4 | L3MBTL1 3357/4885CYP1A2 321/4885CHRM2 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.