Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9403704 | 0.95 | ALDH1A1 (0.52) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL3746015 | 0.92 | ALDH1A1 (0.49) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL18493299 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL27615767 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL7782947 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL14514418 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL7782945 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL11195047 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL27748674 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL27452191 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286386-A1 | Combinatorial production of nucleotide and nucleoside (XiTP) analogues | INSTITUT PASTEUR | 2010-11-11 | — | — | US | disclosed |
| US-7319148-B2 | Combinatorial production of nucleotide and nucleoside (XiTP) analogues | INSTITUT PASTEUR (FR) | 2008-01-15 | — | — | US | disclosed |
| EP-1780214-A2 | Combinatorial production of nucleotide and nucleoside analogues (XiTP) | INSTITUT PASTEUR (FR) | 2007-05-02 | — | — | EP | disclosed |
| EP-1290006-B1 | Combinatorial production of nucleotide and nucleoside (XITP) analogues | PASTEUR INSTITUT (FR) | 2007-02-21 | — | — | EP | disclosed |
| US-20040023240-A1 | Combinatorial production of nucleotide and nucleoside(xitp)analogues | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2004-02-05 | — | — | US | disclosed |
| EP-1290006-A1 | COMBINATORIAL PRODUCTION OF NUCLEOTIDE AND NUCLEOSIDE (XITP)ANALOGUES | INSTITUT PASTEUR (FR) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096354-A1 | COMBINATORIAL PRODUCTION OF NUCLEOTIDE AND NUCLEOSIDE (XITP)ANALOGUES | INSTITUT PASTEUR (FR) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023240-A1 | Combinatorial production of nucleotide and nucleoside(xitp)analogues | TYMP, PNP, DPYD | ALDH1A1 1635/4885KMT2A 2119/4885TDP1 96/4885 |
| US-20100286386-A1 | Combinatorial production of nucleotide and nucleoside (XiTP) analogues | TYMP, PNP, DPYD | ALDH1A1 2422/4885KMT2A 2224/4885TDP1 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.