Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | LAP3 | P28838 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782945 | 1.00 | ALDH1A1 (0.50) | ALDH1A1SLC15A1IDO1KMT2AMAPK1 | |
| SCHEMBL14514418 | 1.00 | ALDH1A1 (0.50) | ALDH1A1SLC15A1IDO1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL28309925 | 0.98 | SLC15A1 (0.49) | ALDH1A1SLC15A1IDO1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL30461727 | 0.98 | SLC15A1 (0.49) | ALDH1A1SLC15A1IDO1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL28309926 | 0.98 | SLC15A1 (0.49) | ALDH1A1SLC15A1IDO1KMT2AMAPK1 | |
| SCHEMBL27873595 | 0.88 | LTA4H (0.54) | ALDH1A1SLC15A1IDO1KMT2AMAPK1 | |
| SCHEMBL304415 | 0.88 | LTA4H (0.54) | ALDH1A1SLC15A1IDO1KMT2AMAPK1 | |
| SCHEMBL169622 | 0.88 | LTA4H (0.54) | ALDH1A1SLC15A1IDO1KMT2AMAPK1 | |
| SCHEMBL1264374 | 0.86 | SLC15A1 (0.61) | ALDH1A1SLC15A1IDO1KMT2AMAPK1 | |
| SCHEMBL589203 | 0.86 | SLC15A1 (0.61) | ALDH1A1SLC15A1IDO1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102241674-B | Synthesis method and antitumor activity evaluation of 1,1-dimethyl-beta-carboline-3-formacyl amino acid benzyl ester | UNIV CAPITAL MEDICAL | 2012-09-12 | — | — | CN | claimed |
| CN-101906102-B | Beta-carboline alkaloid derivative, preparation method and application thereof | UNIV CAPITAL MEDICAL | 2012-08-29 | — | — | CN | claimed |
| CN-102241674-A | Synthesis method and antitumor activity evaluation of 1,1-dimethyl-beta-carboline-3-formacyl amino acid benzyl ester | UNIV CAPITAL MEDICAL | 2011-11-16 | — | — | CN | claimed |
| CN-101497615-B | Substituted purine, preparation and use in medicine | ZHEJIANG MED XINCHANG PHARM | 2010-12-15 | — | — | CN | claimed |
| CN-101906102-A | Beta-carboline alkaloid derivative, preparation method and application thereof | UNIV CAPITAL MEDICAL | 2010-12-08 | — | — | CN | claimed |
| CN-101597290-A | β-Ka Lin-3-formyl tryptophyl amino-acid benzyl ester and its production and application | UNIV CAPITAL MEDICAL (CN) | 2009-12-09 | — | — | CN | claimed |
| CN-101597289-A | 2-tryptophyl-beta-tetrahydro carboline-3-formyol amino-acid benzyl ester and its production and application | UNIV CAPITAL MEDICAL (CN) | 2009-12-09 | — | — | CN | claimed |
| CN-101497615-A | Substituted purine, preparation and use in medicine | XINCHANG PHARMACEUTICAL FACTORY ZHEJIANG MEDICINE CO LTD (CN) | 2009-08-05 | — | — | CN | claimed |
| CN-120058840-A | 2-Asn-tetrahydroisoquinoline-3S-formyl-Ala, and preparation and application thereof | 首都医科大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-120058839-A | 2-Asn-tetrahydroisoquinoline-3S-formyl-Leu, and preparation and application thereof | 首都医科大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-117510578-B | TNF-alpha inhibitor 2-Asn-tetrahydroisoquinoline-3S-formyl-AA, preparation and application | 首都医科大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-117567553-B | 2-Thr-dihydroisoquinoline-3S-formyl-AA as IL-2 agonist, and preparation and antitumor application thereof | 首都医科大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-117567552-B | Four 2-Thr-tetrahydroisoquinoline-3S-formyl-AA compounds of IL-2 agonist, preparation and application | 首都医科大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-117510575-B | 2-Gly-tetrahydroisoquinoline-3S-formyl-AA compound of IL-10 agonist, and preparation and application thereof | 首都医科大学 | 2025-03-28 | — | — | CN | disclosed |
| US-5935542-A | Cyanphosphonate derivatives and method for their preparation | MONSANTO COMPANY (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1998029422-A1 | CYANOPHOSPHONATE DERIVATIVES | MONSANTO COMPANY (US) | 1998-07-09 | — | — | WO | disclosed |
| WO-1998029419-A1 | CYANOPHOSPHORUS COMPOUNDS AND THEIR PREPARATION | MONSANTO COMPANY (US) | 1998-07-09 | — | — | WO | disclosed |
| US-4272528-A | TREATING HERPES | ABBOTT LABORATORIES (US) | 1981-06-09 | — | — | US | disclosed |
| US-4148788-A | Synthesis of thymosin α1 | HOFFMANN-LA ROCHE INC. (US) | 1979-04-10 | — | — | US | disclosed |
| US-4116951-A | [Asn2 ]-thymosin α1 and analogs thereof | HOFFMANN-LA ROCHE INC. (US) | 1978-09-26 | — | — | US | disclosed |