Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053855 | 1.00 | LMNA (0.86) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL525391 | 1.00 | LMNA (0.86) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL20983223 | 1.00 | LMNA (0.86) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| Octyldodecanol SCHEMBL21295571 | 1.00 | LMNA (0.86) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL22462335 | 1.00 | LMNA (0.86) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8970052 | 1.00 | LMNA (0.86) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL20983220 | 1.00 | LMNA (0.86) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL22211645 | 1.00 | LMNA (0.86) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL22462334 | 1.00 | LMNA (0.86) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL4844608 | 1.00 | LMNA (0.86) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833995-B2 | Blood flow promoters for cauda equina tissues | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-2102289-A2 | ENCAPSULATED COLORANTS FOR WATERBORNE COATING COMPOSITIONS SYSTEM KIT AND METHOD | Akzo Nobel Paints LLC (US) | 2009-09-23 | — | — | EP | disclosed |
| WO-2007115335-A2 | ENCAPSULATED COLORANTS FOR WATERBORNE COATING COMPOSITIONS SYSTEM KIT AND METHOD | THE GLIDDEN COMPANY (US) | 2007-10-11 | — | — | WO | disclosed |
| US-20070129327-A1 | Blood flow promoters for cauda equina tissues | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129327-A1 | Blood flow promoters for cauda equina tissues | PTGFR, PTGIS, PTGIR | LMNA 1814/4885ALDH1A1 427/4885HSD17B10 1440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.