Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23321813 | 0.95 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23321938 | 0.93 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23322152 | 0.93 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23321760 | 0.93 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23322193 | 0.93 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23321970 | 0.93 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23322009 | 0.93 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23322271 | 0.93 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23321802 | 0.93 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23321956 | 0.93 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140050917-A1 | LAMINATES OF UV CURABLE ACRYLATES AND SILANE PRIMERS HAVING GOOD ADHESION TO SILICEOUS SURFACES | NANOFILM LTD. (US) | 2014-02-20 | — | — | US | claimed |
| US-11807758-B2 | Siloxane polymer and method of producing siloxane polymer | JNC CORPORATION (JP) | 2023-11-07 | — | — | US | disclosed |
| US-11377455-B2 | Preparation of organosilicon compound having (meth)acryloyloxy group | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-07-05 | — | — | US | disclosed |
| US-20210238419-A1 | SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER | JNC CORPORATION (JP) | 2021-08-05 | — | — | US | disclosed |
| US-20210139515-A1 | Preparation of Organosilicon Compound Having (Meth)acryloyloxy Group | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-05-13 | — | — | US | disclosed |
| EP-3819301-A1 | PREPARATION OF ORGANOSILICON COMPOUND HAVING (METH)ACRYLOYLOXY GROUP | Shin-Etsu Chemical Co., Ltd. (JP) | 2021-05-12 | — | — | EP | disclosed |
| CN-104974184-B | preparation of silazane Compounds | 信越化学工业株式会社 | 2019-12-06 | — | — | CN | disclosed |
| EP-2930177-B1 | PREPARATION OF SILAZANE COMPOUND | SHINETSU CHEMICAL CO (JP) | 2018-04-25 | — | — | EP | disclosed |
| US-9416147-B2 | Preparation of silazane compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-08-16 | — | — | US | disclosed |
| EP-2930177-A1 | Preparation of silazane compound | Shin-Etsu Chemical Co., Ltd. (JP) | 2015-10-14 | — | — | EP | disclosed |
| US-20150284414-A1 | PREPARATION OF SILAZANE COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-10-08 | — | — | US | disclosed |
| US-20140050917-A1 | LAMINATES OF UV CURABLE ACRYLATES AND SILANE PRIMERS HAVING GOOD ADHESION TO SILICEOUS SURFACES | NANOFILM LTD. (US) | 2014-02-20 | — | — | US | disclosed |
| US-7834120-B2 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-1645560-B1 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHINETSU CHEMICAL CO (JP) | 2008-05-28 | — | — | EP | disclosed |
| EP-1645560-A1 | Monofunctional monomer having cage oligosiloxane structure and method of making | Shin-Etsu Chemical Co., Ltd. (JP) | 2006-04-12 | — | — | EP | disclosed |
| US-20060074213-A1 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-04-06 | — | — | US | disclosed |
| US-6307081-B1 | MACROMONOMER HAS ONE OR MORE SILICON-BONDED HYDROGEN ATOMS AT ONE MOLECULAR CHAIN TERMINAL, AND ONE OR MORE ALIPHATICALLY UNSATURATED SILICON-BONDED ORGANIC GROUPS AT THE OTHER MOLECULAR CHAIN TERMINAL. | DOW CORNING SILICONE COMPANY, LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| US-5852153-A | Trimethylsiloxy group-containing polysiloxane and a process for producing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-12-22 | — | — | US | disclosed |
| US-5693735-A | Trimethylsiloxy group-containing polysiloxane and a process for producing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11377455-B2 | Preparation of organosilicon compound having (meth)acryloyloxy group | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MMAB, ACR | TSHR 1239/4885THRB 2877/4885POLB 1464/4885 |
| US-20210139515-A1 | Preparation of Organosilicon Compound Having (Meth)acryloyloxy Group | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MMAB, ACR | TSHR 1250/4885THRB 2844/4885POLB 1427/4885 |
| US-20150284414-A1 | PREPARATION OF SILAZANE COMPOUND | SLTM, SKP2, BCAT2 | TSHR 4559/4885THRB 4315/4885POLB 1964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.