⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18167350 | 0.78 | — | — | |
| SCHEMBL3827018 | 0.78 | — | — | |
| SCHEMBL11880037 | 0.77 | — | — | |
| SCHEMBL6895338 | 0.77 | CA1 (0.39) | — | |
| SCHEMBL16178741 | 0.77 | SLC1A3 (0.33) | — | |
| Ethylmalonate SCHEMBL107241 | 0.76 | — | — | |
| SCHEMBL11854937 | 0.76 | — | — | |
| SCHEMBL7447331 | 0.76 | — | — | |
| SCHEMBL6896640 | 0.75 | SLC7A5 (0.50) | — | |
| SCHEMBL14579036 | 0.75 | GPR84 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | claimed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | claimed |
| US-11981964-B2 | Substituted coumarin dyes and uses as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED (GB) | 2024-05-14 | — | — | US | disclosed |
| EP-2699557-B1 | 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2017-08-16 | — | — | EP | disclosed |
| US-9511073-B2 | Aromatic amides and uses thereof | TAXIS PHARMACEUTICALS, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-8841077-B2 | Biomarkers for amyotrophic lateral sclerosis and methods using the same | MASSACHUSETTS GENERAL HOSPITAL (US) | 2014-09-23 | — | — | US | disclosed |
| US-20140135332-A1 | AROMATIC AMIDES AND USES THEREOF | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2014-05-15 | — | — | US | disclosed |
| EP-2699557-A1 | AROMATIC AMIDES AND USES THEREOF | Biota Scientific Management Pty Ltd (AU) | 2014-02-26 | — | — | EP | disclosed |
| US-20130309697-A1 | BIOMARKERS FOR PROSTATE CANCER AND METHODS USING THE SAME | MITCHELL MATTHEW W (US) | 2013-11-21 | — | — | US | disclosed |
| EP-2657705-A2 | Biomarkers for prostate cancer and methods using the same | Metabolon Inc. (US) | 2013-10-30 | — | — | EP | disclosed |
| US-8518650-B2 | Biomarkers for prostate cancer and methods using the same | METABOLON, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| EP-2560006-A2 | Biomarkers for prostate cancer and methods using the same | Metabolon Inc. (US) | 2013-02-20 | — | — | EP | disclosed |
| WO-2012142671-A1 | AROMATIC AMIDES AND USES THEREOF | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2012-10-26 | — | — | WO | disclosed |
| EP-2061899-B1 | BIOMARKERS FOR PROSTATE CANCER AND METHODS USING THE SAME | METABOLON INC (US) | 2012-08-29 | — | — | EP | disclosed |
| US-20100292331-A1 | Biomarkers for Prostate Cancer and Methods Using the Same | METABALON, INC. (US) | 2010-11-18 | — | — | US | disclosed |
| US-20070298998-A1 | Biomarkers for amyotrophic lateral sclerosis and methods using the same | METABOLON, INC. (US) | 2007-12-27 | — | — | US | disclosed |