Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 3/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7624329 | 0.80 | SLC7A5 (0.54) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL6897228 | 0.80 | SLC7A5 (0.54) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| Hydroxyamine SCHEMBL20817080 | 0.79 | SLC7A5 (0.59) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL1200181 | 0.79 | RNPEP (0.57) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL6888141 | 0.79 | MME (0.47) | SLC7A5ALDH1A1MME | |
| SCHEMBL4716423 | 0.77 | ALDH1A1 (0.42) | SLC7A5ALDH1A1MMEMEN1LMNA | |
| SCHEMBL3746470 | 0.75 | — | — | |
| SCHEMBL14859907 | 0.74 | SLC7A5 (0.46) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL180035 | 0.72 | RNPEP (0.50) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 | |
| SCHEMBL2474901 | 0.70 | RNPEP (0.48) | SLC7A5RNPEPSLC1A3SLC1A2CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | claimed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | claimed |