Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 5/20 | 0.41 |
| ▸ | CBX7 | O95931 | 4/20 | 0.41 |
| ▸ | CDYL2 | Q8N8U2 | 4/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3746585 | 1.00 | SCN1A (0.51) | SCN1ASCN5ASCN9AHSD11B1PLD1 | |
| SCHEMBL13980437 | 0.83 | CYP3A4 (0.47) | HSD11B1CHRM4CHRM5CHRM1TNKS | |
| SCHEMBL3637418 | 0.83 | CYP3A4 (0.47) | HSD11B1CHRM4CHRM5CHRM1TNKS | |
| SCHEMBL1834402 | 0.82 | CHRM1 (0.63) | HSD11B1PLD1CHRM4CHRM5CHRM1 | |
| SCHEMBL1834401 | 0.82 | CHRM1 (0.63) | HSD11B1PLD1CHRM4CHRM5CHRM1 | |
| SCHEMBL30197467 | 0.82 | CHRM1 (0.63) | HSD11B1PLD1CHRM4CHRM5CHRM1 | |
| SCHEMBL3749221 | 0.82 | CHRM2 (0.40) | CHRM4CHRM5CHRM1CHRM2CHRM3 | |
| SCHEMBL3758792 | 0.82 | CHRM2 (0.40) | CHRM4CHRM5CHRM1CHRM2CHRM3 | |
| SCHEMBL3639898 | 0.82 | C5AR1 (0.52) | — | |
| SCHEMBL3758795 | 0.82 | CHRM2 (0.40) | CHRM4CHRM5CHRM1CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292214-A1 | Compounds with Antiparasitic Activity, Applications thereof to the Treatment of Infectious Diseases Caused by Apicomplexans | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2010-11-18 | — | — | US | claimed |
| US-20100292214-A1 | Compounds with Antiparasitic Activity, Applications thereof to the Treatment of Infectious Diseases Caused by Apicomplexans | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2010-11-18 | — | — | US | disclosed |
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292214-A1 | Compounds with Antiparasitic Activity, Applications thereof to the Treatment of Infectious Diseases Caused by Apicomplexans | ABCB11, TPP1, ABCB1 | SCN1A 3542/4885SCN5A 3449/4885SCN9A 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.