Formic Acid

Formic Acid

SCHEMBL3746598

CN1CCN(C(C(=O)NNc2cc(Cl)cc(Cl)c2)c2ccc(OC(F)(F)F)cc2)CC1.O=CO

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 1/20 0.49
CCR3 P51677 2/20 0.44
ABL1 P00519 1/20 0.43
RAPGEF3 O95398 2/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ATM Q13315 1/20 0.40
NPY2R P49146 1/20 0.40
EPHX2 P34913 2/20 0.40
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
PRCP P42785 1/20 0.39
CCR6 P51684 2/20 0.37
ABCB1 P08183 1/20 0.37
P2RY1 P47900 1/20 0.37
GPR139 Q6DWJ6 1/20 0.36
ITGB1 P05556 1/20 0.36
ITGA4 P13612 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3640765 0.96 GHSR (0.52) GHSRCCR3ABL1RAPGEF3MEN1
Formic Acid SCHEMBL3737845 0.82 GHSR (0.49) GHSRCCR3RAPGEF3MEN1KMT2A
SCHEMBL3639648 0.79 CLK1 (0.46) GHSRCCR3MEN1KMT2AALDH1A1
Formic Acid SCHEMBL3746258 0.78 GHSR (0.43) GHSRCCR3MEN1KMT2AALDH1A1
SCHEMBL3639856 0.77 GHSR (0.52) GHSRCCR3RAPGEF3MEN1KMT2A
Formic Acid SCHEMBL3737752 0.76 GHSR (0.66) GHSRCCR3NPY2RALDH1A1LMNA
SCHEMBL3638220 0.76 GHSR (0.53) GHSRCCR3MEN1KMT2ANPY2R
Formic Acid SCHEMBL3745969 0.76 GHSR (0.45) GHSRCCR3ALDH1A1LMNAABCB1
SCHEMBL3639852 0.75 GHSR (0.62) GHSRMEN1KMT2ALMNAABCB1
SCHEMBL3743236 0.75 GAA (0.55) GHSRKMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286152-A1 N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR GLAXO GROUP LIMITED (GB) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286152-A1 N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR GIPR, GHSR, GLP1R GHSR 2/4885CCR3 3769/4885ABL1 3408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.