Formic Acid

Formic Acid

SCHEMBL3737845

CN1CCN(C(C(=O)NNc2cc(Cl)cc(Cl)c2)c2ccc3ccccc3c2)CC1.O=CO

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 1/20 0.49
ABCB1 P08183 9/20 0.44
ALDH1A1 P00352 3/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
CCR3 P51677 2/20 0.41
RAPGEF3 O95398 1/20 0.37
RAPGEF4 Q8WZA2 1/20 0.37
SLC1A3 P43003 2/20 0.37
SLC1A2 P43004 2/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
SLC1A1 P43005 1/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3639856 0.96 GHSR (0.52) GHSRABCB1ALDH1A1LMNACYP1A2
Formic Acid SCHEMBL3746258 0.86 GHSR (0.43) GHSRABCB1ALDH1A1LMNACYP1A2
SCHEMBL3639648 0.85 CLK1 (0.46) GHSRALDH1A1LMNACYP1A2CCR3
SCHEMBL13044524 0.85 GHSR (0.48) GHSRABCB1ALDH1A1LMNACYP1A2
Formic Acid SCHEMBL3636056 0.83 GHSR (0.55) GHSRABCB1ALDH1A1LMNACYP2C19
Formic Acid SCHEMBL3740718 0.83 GHSR (0.48) GHSRABCB1ALDH1A1LMNACCR3
Formic Acid SCHEMBL3745969 0.83 GHSR (0.45) GHSRABCB1ALDH1A1LMNACYP1A2
SCHEMBL3638220 0.82 GHSR (0.53) GHSRABCB1ALDH1A1LMNACCR3
Formic Acid SCHEMBL3746598 0.82 GHSR (0.49) GHSRABCB1ALDH1A1LMNACCR3
Formic Acid SCHEMBL3741661 0.82 GHSR (0.47) GHSRABCB1ALDH1A1LMNACCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286152-A1 N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR GLAXO GROUP LIMITED (GB) 2010-11-11 US claimed
US-20100286152-A1 N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR GLAXO GROUP LIMITED (GB) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286152-A1 N-PHENYL HYDRAZIDES AS MODULATORS OF THE GHRELIN RECEPTOR GIPR, GHSR, GLP1R GHSR 2/4885ABCB1 2178/4885ALDH1A1 2645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.