SCHEMBL3746869

SCHEMBL3746869

C=CC(=O)OCCSc1cccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
HDAC9 Q9UKV0 1/20 0.43
HDAC5 Q9UQL6 1/20 0.43
HPGD P15428 7/20 0.39
LMNA P02545 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
POLB P06746 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ALDH1A1 P00352 8/20 0.39
TSHR P16473 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8028277 0.92 THRB (0.44) THRBHDAC3HDAC4HDAC1HDAC7
SCHEMBL8044874 0.91 TSHR (0.46) THRBHDAC3HDAC4HDAC1HDAC7
SCHEMBL7712533 0.86 THRB (0.56) THRBHPGDKMT2APOLBALDH1A1
SCHEMBL5184316 0.82 THRB (0.51) THRBHPGDKMT2APOLBALDH1A1
SCHEMBL28790322 0.81 HDAC3 (0.39) THRBHDAC3HDAC4HDAC1HDAC7
SCHEMBL24565143 0.79 THRB (0.49) THRBHPGDLMNAKMT2APOLB
SCHEMBL3746865 0.79 THRB (0.41) THRBHPGDLMNAMEN1KMT2A
SCHEMBL23088979 0.79 THRB (0.41) THRBHPGDLMNAMEN1KMT2A
SCHEMBL23088945 0.79 THRB (0.40) THRBHDAC4HPGDALDH1A1TSHR
SCHEMBL13134301 0.79 THRB (0.46) THRBHPGDLMNAKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020204284-A1 PAINT COMPOSITION COMPRISING QUANTUM DOTS OR MANUFACTURING METHOD THEREFOR 주식회사 네모엘텍 2020-10-08 WO claimed
US-9368736-B2 Flexible display apparatus SAMSUNG DISPLAY CO, LTD. (KR) 2016-06-14 US claimed
US-20150115229-A1 FLEXIBLE DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2015-04-30 US claimed
US-20090197986-A1 Polymerizable optical composition, optical sheet and method for making the optical sheet EFUN TECHNOLOGY CO., LTD. (TW) 2009-08-06 US claimed
EP-1954732-A1 COMPOSITIONS FOR BRIGHTNESS ENHANCING FILMS General Electric Company (US) 2008-08-13 EP claimed
WO-2007001811-A1 COMPOSITIONS FOR BRIGHTNESS ENHANCING FILMS GENERAL ELECTRIC COMPANY (US) 2007-01-04 WO claimed
US-20060293463-A1 Compositions for brightness enhancing films GENERAL ELECTRIC COMPANY 2006-12-28 US claimed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO claimed
US-11505653-B2 Compositions and methods of making a polymerized composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-11-22 US disclosed
CN-115167075-A Photopolymer and grating initiated by disperse dye macromolecules and preparation method thereof 杭州光粒科技有限公司 2022-10-11 CN disclosed
CN-111372959-B Photopolymerizable compositions, articles, and methods comprising a urethane component and a monofunctional reactive diluent 3M创新有限公司 2022-09-02 CN disclosed
CN-114585604-A Dicarboxylic acid compound, inorganic particle treated with dicarboxylic acid compound, and composition thereof 3M创新有限公司 2022-06-03 CN disclosed
CN-112759959-B Photopolymer composition and optical grating 杭州光粒科技有限公司 2022-04-29 CN disclosed
CN-113840886-A Composition comprising styrene-isoprene block copolymer and ethylenically unsaturated monomer 3M创新有限公司 2021-12-24 CN disclosed
EP-1869509-A2 LIGHT MANAGEMENT FILMS WITH ZIRCONIA PARTICLES 3M Innovative Properties Company (US) 2007-12-26 EP disclosed
WO-2007001811-A1 COMPOSITIONS FOR BRIGHTNESS ENHANCING FILMS GENERAL ELECTRIC COMPANY (US) 2007-01-04 WO disclosed
US-20060293463-A1 Compositions for brightness enhancing films GENERAL ELECTRIC COMPANY 2006-12-28 US disclosed
WO-2006098899-A2 LIGHT MANAGEMENT FILMS WITH ZIRCONIA PARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-09-21 WO disclosed
US-20060204745-A1 Light management films with zirconia particles 3M INNOVATIVE PROPERTIES COMPANY 2006-09-14 US disclosed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO disclosed