Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 5/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | ATP1A1 | P05023 | 6/20 | 0.33 |
| ▸ | ATP1B1 | P05026 | 6/20 | 0.33 |
| ▸ | ATP1A3 | P13637 | 6/20 | 0.33 |
| ▸ | ATP1B2 | P14415 | 6/20 | 0.33 |
| ▸ | ATP1A2 | P50993 | 6/20 | 0.33 |
| ▸ | ATP1B3 | P54709 | 6/20 | 0.33 |
| ▸ | FXYD2 | P54710 | 6/20 | 0.33 |
| ▸ | ATP1A4 | Q13733 | 6/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13041057 | 1.00 | PHGDH (0.34) | PHGDHP2RY1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL19259714 | 0.88 | PTGS2 (0.33) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL19259715 | 0.88 | PTGS2 (0.33) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL27755636 | 0.76 | P2RY1 (0.35) | PHGDHP2RY1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL16386822 | 0.75 | DDB1 (0.42) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL20558944 | 0.73 | MAP4K4 (0.38) | — | |
| SCHEMBL20558946 | 0.73 | MAP4K4 (0.38) | — | |
| SCHEMBL19034289 | 0.73 | RAB9A (0.40) | — | |
| SCHEMBL20558940 | 0.73 | MAP4K4 (0.38) | — | |
| SCHEMBL16088972 | 0.73 | RAB9A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100279936-A1 | SUBSTITUTED ACETYLENIC COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279936-A1 | SUBSTITUTED ACETYLENIC COMPOUNDS USEFUL FOR THE TREATMENT OF DISEASES | C1R, C3AR1, PTH1R | PHGDH 2235/4885P2RY1 1582/4885ATP1A1 2172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.