Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 10/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 9/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.43 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3739617 | 0.97 | HTR2A (0.43) | FEN1ALOX5APHTR2AARCHEK1 | |
| SCHEMBL3749818 | 0.95 | HTR2A (0.42) | FEN1ALOX5APHTR2AARCHEK1 | |
| SCHEMBL3743094 | 0.94 | HTR2A (0.39) | FEN1ALOX5APHTR2AARCHEK1 | |
| SCHEMBL293119 | 0.79 | KCNJ1 (0.36) | HTR2AAR | |
| SCHEMBL19614567 | 0.78 | FEN1 (0.42) | FEN1ALOX5APHTR2AHCRTR1HCRTR2 | |
| SCHEMBL17729508 | 0.76 | HTR2A (0.39) | FEN1ALOX5APHTR2AHCRTR1HCRTR2 | |
| SCHEMBL17202931 | 0.74 | HTR2A (0.40) | FEN1ALOX5APHTR2AARHCRTR1 | |
| SCHEMBL29058360 | 0.74 | OPRL1 (0.40) | FEN1ALOX5APHTR2AHCRTR1HCRTR2 | |
| SCHEMBL2959996 | 0.70 | KDM4E (0.44) | AR | |
| SCHEMBL7961132 | 0.70 | ALDH1A1 (0.48) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834039-B2 | Oxadiazole compounds | ABBOTT LABORATORIES (US) | 2010-11-16 | — | — | US | disclosed |