Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 3/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3747281 | 0.82 | CYP17A1 (0.56) | SHBGCYP19A1CYP3A4ALDH1A1CYP17A1 | |
| SCHEMBL3744154 | 0.82 | CYP17A1 (0.56) | SHBGCYP19A1CYP3A4ALDH1A1CYP17A1 | |
| SCHEMBL3753990 | 0.79 | SHBG (0.71) | SHBGCYP19A1CYP3A4ALDH1A1CYP17A1 | |
| SCHEMBL3753985 | 0.79 | SHBG (0.71) | SHBGCYP19A1CYP3A4ALDH1A1CYP17A1 | |
| SCHEMBL3746389 | 0.78 | CYP19A1 (0.57) | SHBGCYP19A1CYP3A4ALDH1A1CYP17A1 | |
| SCHEMBL3748864 | 0.76 | SHBG (0.53) | SHBGCYP19A1CYP3A4ALDH1A1MEN1 | |
| SCHEMBL3749070 | 0.76 | SHBG (0.57) | SHBGCYP19A1CYP3A4ALDH1A1CYP17A1 | |
| SCHEMBL3748477 | 0.76 | SHBG (0.57) | SHBGCYP19A1CYP3A4ALDH1A1CYP17A1 | |
| SCHEMBL3748812 | 0.75 | CYP19A1 (0.57) | CYP19A1CYP3A4ALDH1A1LMNACYP2C9 | |
| SCHEMBL7738486 | 0.74 | SHBG (0.78) | SHBGCYP19A1CYP3A4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292184-A1 | 17BETA-CYANO-19-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE | BAYER SCHERING PHARMA AG (DE) | 2010-11-18 | — | — | US | claimed |
| US-20100292184-A1 | 17BETA-CYANO-19-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE | BAYER SCHERING PHARMA AG (DE) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292184-A1 | 17BETA-CYANO-19-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE | HSD17B11, HSD17B7, NR5A1 | SHBG 24/4885CYP19A1 14/4885CYP3A4 166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.