SCHEMBL374911

SCHEMBL374911

CCN(CC)c1ccc(N=O)c(O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 14/20 0.53
ALDH1A1 P00352 14/20 0.53
KDM4E B2RXH2 7/20 0.53
MEN1 O00255 6/20 0.53
KMT2A Q03164 6/20 0.53
LMNA P02545 4/20 0.53
TDP1 Q9NUW8 2/20 0.53
CRHBP P24387 1/20 0.53
CRHR2 Q13324 1/20 0.53
RAB9A P51151 2/20 0.52
GAA P10253 5/20 0.50
SMN1; SMN2 Q16637 5/20 0.50
HTT P42858 3/20 0.50
NPC1 O15118 1/20 0.50
HPGD P15428 2/20 0.49
BLM P54132 1/20 0.49
THRB P10828 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
MAPK1 P28482 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29740108 1.00 MAPT (0.53) MAPTALDH1A1KDM4EMEN1KMT2A
Hydrochloric Acid SCHEMBL103959 0.98 MAPT (0.51) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL29203833 0.90 MAPT (0.45) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL15517674 0.86 ALDH1A1 (0.49) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL27822003 0.85 MAPT (0.41) MAPTALDH1A1KDM4EMEN1KMT2A
Syringol SCHEMBL28068355 0.85 MAPT (0.46) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL7596475 0.83 ALDH1A1 (0.51) MAPTALDH1A1KDM4EMEN1KMT2A
Hydrochloric Acid SCHEMBL7593140 0.82 ALDH1A1 (0.50) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL29406852 0.82 MAPT (0.42) MAPTALDH1A1KDM4EMEN1KMT2A
SCHEMBL2904153 0.82 MAPT (0.42) MAPTALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 365 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113603654-B Difunctional fluorescent probe for detecting lipid droplets and/or protein aggregates as well as preparation method and application thereof 江苏大学 2022-07-22 CN claimed
CN-111072584-B Near-infrared fluorescent small molecule probe and preparation and application thereof 南京科技职业学院 2022-06-24 CN claimed
CN-113603654-A Difunctional fluorescent probe for detecting lipid droplets and/or protein aggregates and preparation method and application thereof 江苏大学 2021-11-05 CN claimed
CN-111072584-A Near-infrared fluorescent small molecule probe and preparation and application thereof 南京科技职业学院 2020-04-28 CN claimed
CN-111051468-B Homogeneous anaerobically stable quantum dot concentrates 昭荣化学工业株式会社 2024-06-04 CN disclosed
CN-114773361-B N-heteronile erythronium salt compound and preparation method and application thereof 山东第一医科大学(山东省医学科学院) 2023-04-11 CN disclosed
CN-110774776-B Method of forming electrically conductive three-dimensional articles 施乐公司 2023-04-04 CN disclosed
US-11584646-B2 Homogeneous anaerobically stable quantum dot concentrates NANOSYS, INC. (US) 2023-02-21 US disclosed
US-11492359-B2 Near-infrared nerve-sparing fluorophores OREGON HEALTH & SCIENCE UNIVERSITY (US) 2022-11-08 US disclosed
CN-113603654-B Difunctional fluorescent probe for detecting lipid droplets and/or protein aggregates as well as preparation method and application thereof 江苏大学 2022-07-22 CN disclosed
CN-113603654-B Difunctional fluorescent probe for detecting lipid droplets and/or protein aggregates as well as preparation method and application thereof 江苏大学 2022-07-22 CN disclosed
CN-111072584-B Near-infrared fluorescent small molecule probe and preparation and application thereof 南京科技职业学院 2022-06-24 CN disclosed
EP-1213328-A1 Oxazine derivatives Evotec OAI AG (DE) 2002-06-12 EP disclosed
WO-2002020670-A1 OXAZINE DERIVATIVES EVOTEC OAI AG (DE) 2002-03-14 WO disclosed
US-6336963-B1 INK COMPOSITION COMPRISING INK VEHICLE COMPRISING FIRST NITRILE COMPOUND HAVING FIRST VISCOSITY AT MELT TEMPERATURE, VISCOSITY MODIFIER COMPRISING SECOND NITRILE COMPOUND HAVING LOWER VISCOSITY AT MELT TEMPERATURE, COLORANT XEROX CORPORATION 2002-01-08 US disclosed
US-6284889-B1 E.G, 9-(N-(N-HEPTYL)-N-(2-HYDROXYETHYL)AMINO)BENZO(D)ISOTHIAZOLO(3, 3A, 4-AB)PHEN-7,12-OXAZINE 4-DIOXIDE. SIEMENS AKTIENGESELLSCHAFT (DE) 2001-09-04 US disclosed
EP-0943661-A2 Chromophoric compounds and their preparation process SIEMENS AKTIENGESELLSCHAFT (DE) 1999-09-22 EP disclosed
EP-0324786-A1 PHOTOCHROMIC SPIRO(INDOLINE) BENZOXAZINES AND ARTICLES CONTAINING THE SAME. PPG INDUSTRIES INC (US) 1989-07-26 EP disclosed
EP-0324786-A4 PHOTOCHROMIC SPIRO(INDOLINE) BENZOXAZINES AND ARTICLES CONTAINING THE SAME. PPG INDUSTRIES INC (US) 1989-06-26 EP disclosed
WO-1988002371-A1 PHOTOCHROMIC SPIRO(INDOLINE) BENZOXAZINES AND ARTICLES CONTAINING THE SAME PPG INDUSTRIES, INC. (US) 1988-04-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11492359-B2 Near-infrared nerve-sparing fluorophores NTRK1, PMP22, GAP43 MAPT 636/4885ALDH1A1 813/4885KDM4E 2244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.