Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160235 | 0.82 | SLC1A3 (0.59) | MMESLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL2820939 | 0.82 | SLC1A3 (0.59) | MMESLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL7402563 | 0.82 | SLC1A3 (0.59) | MMESLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL13456454 | 0.81 | F10 (0.54) | SLC1A3SLC1A2SLC1A1ALDH1A1HPGD | |
| SCHEMBL3805077 | 0.79 | F10 (0.43) | SLC1A3SLC1A2SLC1A1MAPTF10 | |
| Hydrochloric Acid SCHEMBL2828492 | 0.79 | F10 (0.42) | SLC1A3SLC1A2SLC1A1MAPTF10 | |
| SCHEMBL16821240 | 0.78 | SLC1A3 (0.49) | MMESLC1A3SLC1A2SLC1A1ACE | |
| SCHEMBL6830160 | 0.78 | SLC1A3 (0.49) | MMESLC1A3SLC1A2SLC1A1ACE | |
| SCHEMBL8346530 | 0.78 | F2 (0.57) | F10F2 | |
| SCHEMBL2167336 | 0.78 | TMPRSS11D (0.51) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150174021-A1 | COSMETIC COMPOSITION COMPRISING BENZYLSULFONYL-D-SER-HOMOPHE-(4-AMIDINO-BENZYLAMIDE) AND A POLYALCOHOL | DSM IP ASSETS B.V. (NL) | 2015-06-25 | — | — | US | disclosed |
| US-8476306-B2 | Urokinase inhibitors, production and use thereof | THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| US-20110065799-A1 | UROKINASE INHIBITORS, PRODUCTION AND USE THEREOF | THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) | 2011-03-17 | — | — | US | disclosed |
| US-7838560-B2 | for the therapy, prophylaxis and diagnosis of a tumor; benzylsulfonyl-D-Ser-Glu-4-amidinobenzylamidexTFA | THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) | 2010-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150174021-A1 | COSMETIC COMPOSITION COMPRISING BENZYLSULFONYL-D-SER-HOMOPHE-(4-AMIDINO-BENZYLAMIDE) AND A POLYALCOHOL | PLG, PLAT, PRSS8 | MME 109/4885SLC1A3 3962/4885SLC1A2 3377/4885 |
| US-20110065799-A1 | UROKINASE INHIBITORS, PRODUCTION AND USE THEREOF | PLAU, PLAUR, SERPINE1 | MME 59/4885SLC1A3 4598/4885SLC1A2 4822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.